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Cefuroxime Capsules

Function and Efficacy

This product is a first-generation cephalosporin, which has good antibacterial effect on some strains of Gram-positive cocci such as non-penicillinase-producing and penicillinase-producing Staphylococcus aureus, coagulase-negative Staphylococcus, group A hemolytic Streptococcus, Streptococcus pneumoniae and viridans Streptococcus. Anaerobic Gram-positive bacteria are mostly sensitive to this product, while Bacteroides fragilis is resistant to it. Methicillin-resistant Staphylococci and Enterococci are resistant to this product. The effect of this product on Gram-positive and Gram-negative bacteria is similar to that of cephalexin. This product has a certain effect on Neisseria gonorrhoeae, and is also active against enzyme-producing Neisseria gonorrhoeae; its activity against Haemophilus influenzae is poor.

Ingredients

Cefuroxime

Name Description Content CAS NO. Manufacturer
CefradineIngredients

This product is a first-generation cephalosporin, which has good antibacterial effect on some strains of Gram-positive cocci such as non-penicillinase-producing and penicillinase-producing Staphylococcus aureus, coagulase-negative Staphylococcus, group A hemolytic Streptococcus, Streptococcus pneumoniae and viridans Streptococcus. Anaerobic Gram-positive bacteria are mostly sensitive to this product, while Bacteroides fragilis is resistant to it. Methicillin-resistant Staphylococci and Enterococci are resistant to this product. The effect of this product on Gram-positive and Gram-negative bacteria is similar to that of cephalexin. This product has a certain effect on Neisseria gonorrhoeae, and is also active against enzyme-producing Neisseria gonorrhoeae; its activity against Haemophilus influenzae is poor.

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38821-53-3 27

Appearance

This medicine is a hard capsule, and the contents are white crystalline powder.

Indication

This product is a cephalosporin drug. It has a greater effect on Gram-positive bacteria, Gram-negative bacteria, and Neisseria gonorrhoeae. It is effectively used for acute pharyngitis, tonsillitis, otitis media, bronchitis, pneumonia and other respiratory tract infections, urogenital tract infections, and skin and soft tissue infections caused by sensitive bacteria.

Usage and Dosage

Oral: Adults 0.25-0.5g once, once every 6 hours, the maximum daily dose is 4g. Children's usual dose: 25-50mg/kg per day according to body weight

Adverse Reactions

The adverse reactions of this product are mild and the incidence is low, about 6%. Gastrointestinal reactions such as nausea, vomiting, diarrhea, and upper abdominal discomfort are more common. The incidence of drug rash is about 1% to 3%, pseudomembranous colitis, eosinophilia, and direct Coombs test positive

Precautions

This product is contraindicated in patients who are allergic to cephalosporins or have a history of anaphylactic shock or immediate reaction to penicillin.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: This product can enter the fetal blood circulation through the placenta barrier and can also enter the breast milk. Pregnant and lactating women should use it with caution. Precautions for the elderly: Not yet clear.

Drug Interactions

1. Cephalosporins can delay the excretion of phenytoin sodium in the renal tubules. 2. Phenylbutazone combined with cephalosporin antibiotics can increase renal toxicity. 3. Combined with strong diuretics can increase renal toxicity. 4. Combined with mecillinam, it has a synergistic effect on gram-negative bacteria such as Escherichia coli and Salmonella. 5. Probenecid can delay the excretion of this product.

Storage

Keep in a dark, sealed container and stored in a cool place. Valid for 3 years.

Packaging Specification

0.5g (calculated as C16H19N304S)

Validity Period

24 months.

Manufacturer

Suzhou No.3 Pharmaceutical Factory Co., Ltd.

  • Founded in:

    1981-12-14
  • Address:

    No. 8, Jinzi Road, Fenhu High-tech Industrial Development Zone, Wujiang District, Suzhou
  • Tax NO.:

    91320509137703209P
  • Registered Funds:

    4.2 million yuan
  • Website:

  • Email:

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