Nifedipine extended-release tablets

This product is a calcium influx blocker or slow channel blocker, which blocks calcium ions from entering cells through the channels on the myocardial or vascular smooth muscle membrane, thereby causing the vascular tension of the whole body, including the coronary arteries, to decrease and expand, thus lowering blood pressure. It increases the blood supply of the coronary arteries. On the other hand, it can inhibit myocardial contraction, reduce myocardial work, reduce oxygen demand, and relieve angina pectoris. The therapeutic dose has little effect on the function of the sinoatrial node and atrioventricular node.

The active ingredient of this product is: nifedipine.

This product is a film-coated tablet, which appears yellow after removing the film coating.

Used for various types of hypertension and angina pectoris.

Oral: 10-20 mg once, twice a day. Maximum dose: 40 mg once, 0.12 g a day.

1. Liver: Occasionally, jaundice and elevated glutamate oxaloacetate aminotransferase and glutamate pyruvate aminotransferase may occur. 2. Circulatory system: Occasionally, chest pain, headache, flushing, dizziness, palpitations, decreased blood pressure, lower limb edema may occur. 3. Allergies: Occasionally, allergic symptoms such as measles and itching may occur. 4. Digestive system: Occasionally, abdominal pain, nausea, loss of appetite, constipation may occur. 5. Oral cavity: Gum hypertrophy may occur. 6. Metabolic abnormalities: Occasionally, symptoms of hyperglycemia may occur.

1. It is contraindicated in patients with cardiogenic shock or acute myocardial infarction (within 80 days). 2. It is contraindicated in pregnant women and children.

Precautions for children: Safety and efficacy are not yet clear. Precautions for pregnancy and lactation: Pregnant women are prohibited from using this drug. Precautions for the elderly: After taking this drug, its half-life is prolonged, and Cmax and AUC are increased. Be careful to start taking it from the lowest dose to reduce the incidence of adverse reactions.

1. When used in combination with nitrates, it can control angina attacks and has good tolerance. 2. When used in combination with receptor blockers, most patients have good tolerance and efficacy for this product, but some patients may induce and aggravate hypotension, heart failure and angina. 3. When used in combination with digitalis, it may increase the blood digoxin concentration, suggesting that the blood concentration of digoxin should be monitored when using this product for the first time, adjusting the dose or discontinuing this product. 4. When used in combination with drugs with high protein binding rates, such as dicoumarins, phenytoin sodium, quinidine, quinine, warfarin, etc., the free concentrations of these drugs often change. 5. When used in combination with cimetidine, the peak plasma concentration of this product increases, so pay attention to adjusting the dose. 6. When grapefruit juice is taken with this product, the Cmax and AUC of this product increase.

seal.

10 mg

24 months

Shaanxi Wanshou Pharmaceutical Co., Ltd.

• Founded in:

  1995-09-04

• Address:

  West Jianshe Road, Huayin City, Weinan City, Shaanxi Province

• Tax NO.:

  9161000022052392XU

• Registered Funds:

  5 million yuan

• Website:

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