Metformin Hydrochloride Tablets

The main ingredient of this product is: metformin hydrochloride. Chemical name: 1.1-dimethylbiguanide hydrochloride Molecular weight: C4H11N5?HCl

This product is a sugar-coated or film-coated tablet, which appears white after removing the coating.

For adults, the initial oral dose is 0.25 g at a time, 2-3 times a day, and the dosage can be gradually increased based on the efficacy. The general daily dose is 1-1.5 g, and the maximum daily dose should not exceed 2 g. Taking it during or immediately after a meal can reduce gastrointestinal reactions.

1. Common symptoms include: nausea, vomiting, diarrhea, metallic taste in the mouth. 2. Sometimes there is weakness, tiredness, dizziness, and rash. 3. Although the incidence of lactic acidosis is very low, it should be paid attention to. Clinical manifestations include vomiting, abdominal pain, hyperventilation, mental disorder, and increased lactic acid concentration in the blood that cannot be explained by uremia, ketoacidosis or salicylic acid poisoning. 4. It can reduce the intestinal absorption of vitamin B12, reduce hemoglobin, produce megaloblastic anemia, and also cause malabsorption.

The following conditions should not be used: 1. Type II diabetes with ketoacidosis, liver and kidney dysfunction (serum creatinine exceeds 1.5mg/dl), pulmonary dysfunction, heart failure, acute myocardial infarction, severe infection and trauma, major surgery, and clinical hypotension and hypoxia. 2. Diabetes with severe chronic complications (such as diabetic nephropathy, diabetic fundus lesions). 3. Before foot vein pyelography or arterial pyelography. 4. Alcoholics. 5. Patients with severe heart and lung diseases. 6. Patients with vitamin B12, folic acid and iron deficiency. 7. Patients with poor general condition (such as malnutrition, dehydration).

Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: It is not suitable for pregnant and lactating women. Precautions for the elderly: Elderly patients (65 years old) should use it with caution because of weakened renal function and the dosage should be reduced.

1. When used in combination with insulin, the hypoglycemic effect is enhanced, and the dosage should be adjusted. 2. This product can enhance the anticoagulant effect of anticoagulants (such as warfarin, etc.), which may cause bleeding tendency. 3. Cimetidine can increase the bioavailability of this product and reduce the renal clearance rate, so the dosage of this product should be reduced.

seal.

0.25g*60s

24 months

Guizhou Shengjitang Pharmaceutical Co., Ltd.

• Founded in:

  1996-02-16

• Address:

  Qingzhen City Medical Park, Guiyang City, Guizhou Province

• Tax NO.:

  915201006222407117

• Registered Funds:

  607 million yuan

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