Griseofulvin Tablets

This product has good antibacterial effect on superficial fungi such as Trichophyton, Microsporum, Epidermophyton, etc. It has no antibacterial effect on Candida, Cryptococcus, Histoplasma, Sporothrix, Blastomyces, Coccidioides, etc. This drug inhibits the growth of fungi by interfering with the synthesis of fungal nucleic acids.

Griseofulvin

This product is white or off-white tablets.

This product is suitable for the treatment of various tinea, including tinea capitis, tinea barbae, tinea corporis, tinea cruris, tinea pedis and tinea unguium. The above tinea are caused by Trichophyton crimson, Trichophyton tonsurans, Trichophyton mentagrophytes, Trichophyton interdigitalis, etc., as well as Microsporum audouinensis, Microsporum canis, Microsporum gypseum and Epidermophyton floccosum. This product is not suitable for mild, localized superficial fungal infections and those who have been effective with topical antifungal drugs. Griseofulvin is ineffective against infections such as Candida, Histoplasma, Actinomyces, Sporothrix, Blastomyces, Coccidioides, Nocardia and Cryptococcus, as well as tinea versicolor.

The following is the dosage of microparticles. Adults: 500 mg once every 12 hours for onychomycosis and tinea pedis; 250 mg once every 12 hours or 500 mg once daily for tinea capitis, tinea corporis or tinea cruris. Children: 62.5 to 125 mg once every 12 hours or 125 to 250 mg once daily for children over 2 years old weighing 14 to 23 kg. Children weighing more than 23 kg can take 125 to 250 mg once every 12 hours or 250 to 500 mg once daily.

1 Nervous system headaches are relatively common, with about 10% of patients experiencing headaches, which are severe at first and can be alleviated with continued medication. Other symptoms include drowsiness and fatigue. Occasionally, dizziness, ataxia and peripheral neuritis may occur. 2 Digestive system A small number of patients may experience upper abdominal discomfort, nausea or diarrhea, which are generally mild and tolerated by patients. 3 Allergic reactions About 3% of patients may develop rashes, and occasionally angioedema, persistent urticaria, exfoliative dermatitis, and a small number of patients may develop photosensitive dermatitis. 4 This product may occasionally cause peripheral blood leukopenia, and may occasionally cause hepatotoxicity and proteinuria.

It is contraindicated for patients with porphyria, liver failure, pregnant women and those who are allergic to this product.

Precautions for children: There is a lack of data on the use of this product in children under 2 years old. Precautions for pregnancy and lactation: Animal experiments have shown that this product has teratogenic effects, so it is contraindicated for pregnant women. Women of childbearing age should take contraceptive measures during treatment and continue until 1 month after the end of treatment. Precautions for the elderly: There is no research data on the use of this product in the elderly and its relationship with age.

1. Taking this product with ethanol may cause tachycardia, sweating, skin flushing, etc., so the two should not be used together. 2. When used in combination with anticoagulants such as warfarin and coumarins, this product may enhance liver metabolism and weaken the effect of anticoagulants, so it is necessary to monitor the prothrombin time to adjust the dose. 3. When used in combination with primidone and phenobarbital drugs, the antifungal effect of this product may be weakened, which may be related to the fact that barbiturates reduce the absorption of the drug and the inactivation of this product is accelerated due to the effect on liver enzymes, resulting in a decrease in blood drug concentration. Such drugs should be avoided from being used in combination with this product. 4. The combination of estrogen contraceptives and this product can reduce the effectiveness of oral contraceptives, which may be related to the fact that this product enhances the metabolism of such drugs in the liver, resulting in a decrease in blood drug concentration. The two should be avoided from being used together.

This product is white or off-white tablets.

0.1g

36 months

Guangxi Dahai Sunshine Pharmaceutical Co., Ltd.

• Founded in:

  2012-09-27

• Address:

  No. 1 Shangping Road, Guangxi-ASEAN Economic and Technological Development Zone

• Tax NO.:

  91450100054382235D

• Registered Funds:

  23.8 million yuan

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