Diclofenac sodium eye drops

Pharmacological action: Diclofenac sodium is a non-steroidal anti-inflammatory analgesic derived from phenylacetic acid. Its mechanism of action is to inhibit the activity of cyclooxygenase, thereby blocking the conversion of arachidonic acid to prostaglandins. At the same time, it can also promote the binding of arachidonic acid to triglycerides, reduce the concentration of free arachidonic acid in cells, and indirectly inhibit the synthesis of leukotrienes. Animal experiments have confirmed that prostaglandins are one of the mediators of intraocular inflammation, which can lead to blood-aqueous barrier collapse, vasodilation, increased vascular permeability, leukocyte chemotaxis, non-cholinergic mechanism pupil constriction, etc. Diclofenac sodium is one of the stronger non-steroidal anti-inflammatory drugs, and its inhibitory effect on prostaglandin synthesis is stronger than that of aspirin and indomethacin. Diclofenac sodium eye drops have an effective effect on the blood-aqueous barrier caused by mechanical, chemical, biological and other stimuli.

Diclofenac sodium, its chemical name is: 2-[(2,6-dichlorophenyl)amino]-phenylacetate sodium

This product is a colorless or slightly yellow clear aqueous solution

It is used to treat uveitis, keratitis, scleritis, inhibit the formation of corneal neovascularization, treat inflammatory reactions after intraocular surgery, laser keratoconjunctivitis or various eye injuries, and inhibit the pupillary constriction reaction during cataract surgery; it is used to relieve pain and inflammation after excimer laser keratectomy; it is used for allergic eye diseases such as spring conjunctivitis and seasonal allergic conjunctivitis, prevent and treat inflammation and macular cystoid edema after cataract and intraocular lens surgery, and promote the formation of filtration blebs after glaucoma filtration surgery.

4 to 6 times a day, 1 drop each time; for ophthalmic surgery: 1 drop each time, 3, 2, 1, and 0.5 hours before surgery. Start taking the medication 24 hours after cataract surgery, 4 times a day, and continue for two weeks; start taking the medication 15 minutes after corneal refractive surgery, 4 times a day, and continue for three days

Eye drops may cause short-term burning, stinging, tearing, etc., and very few may have conjunctival congestion and blurred vision. Less than 3% of patients may experience systemic reactions such as fatigue, drowsiness, and nausea.

It is contraindicated for those who are allergic to this product.

Precautions for children: The safety and effects of this product in children have not been investigated. Precautions for pregnancy and lactation: In animal teratogenicity studies, mice were given 5000 times the human topical dose (20 mg/kg/day), and rats and rabbits were given 2500 times (10 mg/kg/day), and no teratogenic effects were found, although these doses have reached toxicity to the mother and fetus. The toxicity of diclofenac sodium to rat mothers is manifested as dystocia, prolonged pregnancy, and decreased fetal weight, growth and survival rate. It has been shown that diclofenac sodium can pass through the placental barrier of rats and mice. However, there are currently no reports of studies in humans, so pregnant women should use it with caution. Precautions for the elderly: This product may induce or aggravate gastrointestinal bleeding, ulcers and perforations in the elderly. It should be used with caution in elderly patients taking diuretics or with extracellular fluid loss.

Not yet clear

Keep in a dark and sealed place. Valid for two years

5ml:5mg

24 months

Hubei Kangzheng Pharmaceutical Co., Ltd.

• Founded in:

  2001-03-06

• Address:

  No. 88, Development 2nd Road, Dongcheng Economic Development Zone, Anlu City, Hubei Province

• Tax NO.:

  91420982726117742M

• Registered Funds:

  12 million yuan

• Website:

  Log in to view

• Email:

  Log in to view