Neomycin Sulfate Tablets

Neomycin sulfate is an aminoglycoside antibiotic. This product has good antibacterial effect on Enterobacteriaceae such as Staphylococcus (methicillin-sensitive strains), Corynebacterium, Escherichia coli, Klebsiella, Proteus, etc., and has poor activity against various groups of Streptococci, Streptococcus pneumoniae, Enterococcus, etc. Pseudomonas aeruginosa and anaerobic bacteria are resistant to this product. Bacteria have partial or complete cross-resistance to streptomycin, neomycin, kanamycin, and gentamicin. Systemic neomycin has significant nephrotoxicity and ototoxicity, so it is currently limited to oral or topical application.

Neomycin Sulfate

This product is white tablets.

Oral administration can be used for: 1. Intestinal infection. 2. It can also be used for intestinal preparation before colon surgery or as an auxiliary treatment for hepatic coma. Neomycin is not suitable for the treatment of systemic infection.

1 Oral administration: 0.25-0.5g (calculated as neomycin) per time for adults, 4 times a day. For adjuvant treatment of hepatic encephalopathy, 0.5-1g per time, once every 6 hours, for 5-6 days. For preparation before colon surgery, 0.5g per hour, for 4 times, followed by 0.5g every 4 hours, for a total of 24 hours. 2 For children, 25-50mg/kg per day, divided into 4 doses.

1. It may cause loss of appetite, nausea, diarrhea, etc., but long-term use (more than 10 weeks) does not affect the synthesis of vitamin K. 2. Hearing loss, tinnitus or fullness in the ears are rarely found; dizziness or unsteady gait; urine volume or urination frequency is significantly reduced or extreme thirst. 3. It may occasionally cause intestinal mucosal atrophy, leading to malabsorption syndrome and fatty diarrhea, or even pseudomembranous enterocolitis.

This product is contraindicated in patients who are allergic to neomycin or other aminoglycoside antibiotics.

Precautions for children: There is a lack of data on the safe use of this product in premature infants and newborns, so it should not be used. Precautions for pregnancy and lactation: Pregnant women should use this product with caution. Lactating women should suspend breastfeeding during medication. Precautions for the elderly: Elderly patients should use this product with caution.

1 Long-term use with oral contraceptives (containing estrogen) may lead to contraceptive failure and increase the incidence of bleeding. 2 Oral neomycin can affect the absorption of digitalis glycosides, fluorouracil, methotrexate, penicillin V, vitamin A or vitamin B12, reducing the efficacy; therefore, the patient's efficacy of digitalis drugs should be closely observed to see if there is a change. When patients taking oral neomycin take colchicine and vitamin A in combination, their vitamin B12 requirements may increase. 3 This product should not be used in combination with other nephrotoxic and ototoxic drugs. 4 When used in combination with neuromuscular blocking drugs, it may increase the neuromuscular blocking effect and lead to skeletal muscle weakness, etc.

Sealed, store in a dry place.

0.1g (100,000 units)

24 months

Jiangsu Jibeier Pharmaceutical Co., Ltd.

• Founded in:

  2001-11-13

• Address:

  Zhenjiang High-tech Industrial Development Park

• Tax NO.:

  913211007317784571

• Registered Funds:

  199.430865 yuan

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