Cefaclor Tablets
Function and Efficacy
This product is a broad-spectrum semi-synthetic cephalosporin antibiotic. Its activity against penicillinase-producing Staphylococcus aureus, group A hemolytic streptococci, viridans streptococci and Staphylococcus epidermidis is the same as that of cefadroxil, and its antibacterial effect against non-enzyme-producing Staphylococcus aureus and pneumococci is 2 to 4 times stronger than that of cefadroxil. Its activity against Gram-negative bacilli, including Escherichia coli and Klebsiella pneumoniae, is stronger than that of cefadroxil, and is similar to that of cefadroxil. Its activity against Proteus mirabilis, Salmonella and Shigella is stronger than that of cefadroxil. 2.9 to 8 mg/L of this product can inhibit all Haemophilus influenzae, including strains resistant to ampicillin. Moraxella catarrhalis and Neisseria gonorrhoeae are very sensitive to this product. Indole-positive Proteus, Serratia, Acinetobacter and Pseudomonas aeruginosa are all resistant to this product. The mechanism of action of this product is to inhibit the synthesis of bacterial cell walls.
Ingredients
Cefaclor
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| CefaclorIngredients |
This product is a broad-spectrum semi-synthetic cephalosporin antibiotic. Its activity against penicillinase-producing Staphylococcus aureus, group A hemolytic streptococci, viridans streptococci and Staphylococcus epidermidis is the same as that of cefadroxil, and its antibacterial effect against non-enzyme-producing Staphylococcus aureus and pneumococci is 2 to 4 times stronger than that of cefadroxil. Its activity against Gram-negative bacilli, including Escherichia coli and Klebsiella pneumoniae, is stronger than that of cefadroxil, and is similar to that of cefadroxil. Its activity against Proteus mirabilis, Salmonella and Shigella is stronger than that of cefadroxil. 2.9 to 8 mg/L of this product can inhibit all Haemophilus influenzae, including strains resistant to ampicillin. Moraxella catarrhalis and Neisseria gonorrhoeae are very sensitive to this product. Indole-positive Proteus, Serratia, Acinetobacter and Pseudomonas aeruginosa are all resistant to this product. The mechanism of action of this product is to inhibit the synthesis of bacterial cell walls. More |
53994-73-3 | 29 |
Appearance
This product is a film-coated tablet, which appears white to slightly yellowish after removing the coating.
Indication
This product is mainly suitable for respiratory system, urinary system, ENT, skin and soft tissue infections caused by sensitive bacteria.
Usage and Dosage
Oral administration. Adults: 0.25g once, 3 times a day. For patients with severe infection, the dose can be doubled, but the total amount per day should not exceed 4g. Or follow the doctor's advice. Children: 20-40mg/kg per day, divided into 3 doses, but the total amount per day should not exceed 1g.
Adverse Reactions
1. Common gastrointestinal reactions: soft stools, diarrhea, stomach discomfort, loss of appetite, nausea, vomiting, heating, etc. 2. Serum sickness-like reactions are more common than other antibiotics, especially in children, with typical symptoms including skin reactions and joint pain. 3. Allergic reactions: rash, urticaria, eosinophilia, vulvar itching, etc. 4. Others: mild increase in serum aminotransferase, urea nitrogen and creatinine, proteinuria, cystic urine, etc.
Precautions
Patients who are allergic to cefaclor and other cephalosporins are contraindicated.
Special Population Medication
Precautions for children: Not clear. Precautions for pregnancy and lactation: 1. Use with caution in pregnant women. 2. This product can be excreted through breast milk, so lactating women should use it with caution or stop breastfeeding. Precautions for the elderly: Elderly patients should adjust the dosage or medication interval according to their renal function under the guidance of a physician.
Drug Interactions
1. The combined use of strong diuretics such as furosemide, ethacrynic acid, bumetanide, anti-tumor drugs such as carmustine, streptozocin, and nephrotoxic drugs such as aminoglycoside antibiotics with this product may increase nephrotoxicity. 2. Clavulanic acid can enhance the antibacterial activity of this product against certain Gram-negative bacteria that are resistant to this product due to the production of β-lactamase. 3. Oral administration of probenecid can delay the excretion of this product.
Storage
Keep away from light, seal tightly, and store in a cool, dark and dry place.
Packaging Specification
0.25g
Validity Period
24 months
Manufacturer
Jiangsu Yabang Qiangsheng Pharmaceutical Co., Ltd.
-
Founded in:
2006-04-06 -
Address:
No. 198, Huacheng Road, Jintan District, Changzhou -
Tax NO.:
91320413786327805B -
Registered Funds:
30 million yuan -
Email: