Benhexyphenidyl hydrochloride tablets
Function and Efficacy
This product is a central anticholinergic anti-Parkinson's disease drug that selectively blocks the cholinergic nerve pathways in the striatum, but has less effect on the periphery, thus helping to restore the balance of dopamine and acetylcholine in the brain of Parkinson's patients and improve the patients' Parkinson's disease symptoms.
Ingredients
The main ingredient of this product is benzhexol hydrochloride, and its chemical name is: α-cyclohexyl-α-phenyl-1-piperidinylpropanol hydrochloride.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Benzhexol hydrochlorideIngredients |
This product is a central anticholinergic anti-Parkinson's disease drug that selectively blocks the cholinergic nerve pathways in the striatum, but has less effect on the periphery, thus helping to restore the balance of dopamine and acetylcholine in the brain of Parkinson's patients and improve the patients' Parkinson's disease symptoms. More |
52-49-3 | 13 |
Appearance
This product is white tablets.
Indication
This drug can be used to treat Parkinson's disease and Parkinson's syndrome. It can also be used for drug-induced extrapyramidal disorders. Its main pharmacological action is to block central cholinergic receptors, weaken the effect of acetylcholine in the substantia nigra-striatum pathway, and reduce the excitability of the reticular formation-thalamus and thalamus-cortical projection system, exerting anticholinergic and anti-tremor effects.
Usage and Dosage
For Parkinson's disease and Parkinson's syndrome, take 1-2 mg (0.5-1 tablet) a day at first, and then increase by 2 mg (1 tablet) every 3-5 days until the best effect is achieved without side effects. Generally, do not exceed 10 mg (5 tablets) a day, divided into 3-4 doses, and must be taken for a long time. The maximum daily dose is 20 mg (10 tablets). For drug-induced extrapyramidal disorders, take 2-4 mg (1-2 tablets) on the first day, divided into 2-3 doses, and then gradually increase to 5-10 mg (2.5-5 tablets) according to needs and tolerance.
Adverse Reactions
Common symptoms include dry mouth, blurred vision, etc., and occasionally tachycardia, nausea, vomiting, urinary retention, constipation, etc. Long-term use may cause drowsiness, depression, memory loss, hallucinations, and clouded consciousness.
Precautions
Patients with glaucoma, urinary retention, and prostatic hypertrophy.
Special Population Medication
Precautions for children: Use with caution. Precautions for pregnancy and lactation: Use with caution. Precautions for the elderly: Long-term use in the elderly is likely to induce glaucoma. People with arteriosclerosis are prone to mental confusion, disorientation, anxiety, hallucinations and psychotic symptoms when taking the commonly used doses of anti-Parkinson's disease drugs. Use with caution.
Drug Interactions
1 When this product is used in combination with ethanol or other central nervous system depressants, the central inhibitory effect can be enhanced. 2 When this product is used in combination with adamantane, anticholinergic drugs, monoamine oxidase inhibitors such as pargyline and procarbazine, the anticholinergic effect can be enhanced and paralytic ileus may occur. 3 When this product is used in combination with monoamine oxidase inhibitors, it can cause hypertension. 4 When this product is used in combination with antacids or adsorbent antidiarrheal agents, the effect of this product can be weakened. 5 When this product is used in combination with chlorpromazine, the latter's metabolism is accelerated, which can reduce its blood drug concentration. 6 When this product is used in combination with cardiac glycosides, the latter can prolong their residence time in the gastrointestinal tract, increase absorption, and be prone to poisoning.
Storage
Keep sealed.
Packaging Specification
2 mg
Validity Period
36 months.
Manufacturer
Tianjin Lisheng Pharmaceutical Co., Ltd.
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Founded in:
1981-06-17 -
Address:
No. 16, Saida North 1st Road, Xiqing Economic Development Zone, Tianjin -
Tax NO.:
91120000103069502J -
Registered Funds:
257.942988 yuan -
Website:
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Email: