Diphenhydramine Hydrochloride Tablets
Function and Efficacy
It is a derivative of ethanolamine. Its antihistamine effect is not as good as promethazine, and its duration of action is also shorter. The two drugs have the same sedative effect, and have local anesthetic, antiemetic and anti-M cholinergic effects. (1) Antihistamine effect: it can compete with histamine released from tissues for H1 receptors on effector cells, thereby stopping allergic reactions; (2) Inhibition of central nervous system activity causes sedative and hypnotic effects; (3) Strengthens the effect of antitussive drugs; (4) It also has anti-vertigo and anti-tremor paralysis effects.
Ingredients
The main ingredient of this product is diphenhydramine hydrochloride, and its chemical name is N,N-dimethyl-2-(diphenylmethoxy)ethylamine hydrochloride.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Diphenhydramine HydrochlorideIngredients |
It has an antihistamine effect and can compete with histamine released from tissues for the H1 receptors on effector cells, thereby stopping allergic reactions; it inhibits central nervous system activity and causes sedative and hypnotic effects; it enhances the effects of antitussive drugs; it has anti-vertigo and anti-tremor paralysis effects; it has local anesthetic, antiemetic and anti-M cholinergic effects. More |
147-24-0 | 31 |
Appearance
This product is a sugar-coated tablet, which appears white after removing the sugar coating.
Indication
It is mainly used for: skin and mucous membrane allergies, such as urticaria, angioedema, allergic rhinitis, pruritus, drug rash, and is also effective for insect bites and contact dermatitis; prevention and treatment of motion sickness, with a strong antiemetic effect; Parkinson's disease and extrapyramidal symptoms; sedation, hypnosis; strengthening the effect of antitussive drugs, suitable for treating coughs caused by colds or allergies.
Usage and Dosage
The usual dose for adults is to take the medicine orally after meals, 25-50 mg (1-2 tablets) at a time, 2-3 times a day.
Adverse Reactions
(1) Common symptoms include: central nervous system depression, ataxia, nausea, vomiting, loss of appetite, etc. (2) Rare symptoms include: shortness of breath, chest tightness, cough, dystonia, etc. There are reports that trismus and laryngeal spasm may occur after administration. (3) Occasionally, it may cause rash, neutropenia, anemia and heart rate disturbances.
Precautions
It is contraindicated for patients with myasthenia gravis, angle-closure glaucoma, prostatic hypertrophy, those who are allergic to this product and excipients, newborns, and premature infants.
Special Population Medication
Precautions for children: It is forbidden to use in newborns and premature infants. Precautions for pregnancy and lactation: (1) Taking this product during pregnancy may increase the incidence of cleft palate, inguinal hernia and urogenital malformations in infants, so pregnant women should use it with caution; (2) A small amount of this product can be excreted in breast milk, so it should not be used by lactating women. Precautions for the elderly: It may cause slow reaction, dizziness, etc.
Drug Interactions
(1) This product can temporarily affect the absorption of barbiturates and sodium sulfacetamide. (2) When used together with sodium para-aminosalicylate, it can reduce the latter's blood concentration. (3) It can enhance the effects of central nervous system depressants.
Storage
Keep sealed.
Packaging Specification
25mg
Validity Period
2 years
Manufacturer
Tianjin Lisheng Pharmaceutical Co., Ltd.
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Founded in:
1981-06-17 -
Address:
No. 16, Saida North 1st Road, Xiqing Economic Development Zone, Tianjin -
Tax NO.:
91120000103069502J -
Registered Funds:
257.942988 yuan -
Website:
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Email: