Anisodamine Hydrobromide Injection
Function and Efficacy
This product is an anticholinergic drug that acts on M-cholinergic receptors. It has obvious peripheral anticholinergic effects, which are similar to or slightly weaker than atropine. It can relax smooth muscles and relieve microvascular spasms, so it has antispasmodic, analgesic and microcirculation improving effects. Its pupil dilation and glandular secretion inhibition effects are 1/20 to 1/10 of atropine. Because it cannot pass through the blood-brain barrier, its central effect is weak. Compared with atropine, it has the advantages of higher selectivity and lower toxicity and side effects.
Ingredients
The chemical name of this product is Scopolia tangutica Maxim, a plant of the Solanaceae family. It is a hydrobromide salt of an alkaloid extracted from the root of Scopolia tangutica Maxim. The structural formula is: (see Scopolia tangutica Maxim hydrobromide tablets), molecular formula: C17H23NO4HBr, molecular weight: 386.29.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| ANISODAMINE HYDROBROMIDEIngredients |
Anticholinergic drugs acting on M-cholinergic receptors have obvious peripheral anticholinergic effects, can relax smooth muscles, relieve microvascular spasms, and thus have antispasmodic, analgesic and microcirculatory effects. Its effect of dilating pupils and inhibiting glandular secretion is 1/20 to 1/10 of that of atropine. Because it cannot pass through the blood-brain barrier, its central effect is weaker. Compared with atropine, it has the advantages of higher selectivity and lower toxicity and side effects. More |
55449-49-5 | 2 |
Appearance
This product is a colorless clear liquid.
Indication
Used for toxic shock, rescue of organophosphorus pesticide poisoning, and relief of smooth muscle spasms and vertigo.
Usage and Dosage
Intramuscular injection: 5-10 mg each time, 1-2 times a day; intravenous injection: ① Infectious toxic shock: The dosage is determined according to the condition, 10-40 mg for adults, 0.3-2 mg per kg of body weight for children, repeated every 10-30 minutes, or 5-10 mg of this product can be added to 200 ml of 5% glucose solution for intravenous drip, and the dosing interval can be extended as the condition improves until the drug is stopped. If the condition does not improve, the dosage can be increased as appropriate. The rescue dosage for organophosphorus poisoning depends on the condition.
Adverse Reactions
Dry mouth, flushed face, mild mydriasis, blurred vision of near objects, etc. Some patients may experience increased heart rate and difficulty urinating, which usually disappear in 1 to 3 hours. There is no cumulative poisoning with long-term use.
Precautions
It is contraindicated in patients with increased intracranial pressure, acute cerebral hemorrhage and glaucoma.
Drug Interactions
Not yet clear.
Storage
Keep in a light-proof and airtight container.
Packaging Specification
1ml:10mg
Manufacturer
Changchun Changqing Pharmaceutical Group Co., Ltd.
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Founded in:
2004-08-02 -
Address:
No. 572, Haikou Road, Changchun Economic and Technological Development Zone -
Tax NO.:
912201011240156770 -
Registered Funds:
20 million yuan -
Email: