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Enalapril Maleate Capsules

Function and Efficacy

This product is an angiotensin converting enzyme inhibitor. After oral administration, it is hydrolyzed into enalaprilat in the body, which strongly inhibits angiotensin converting enzyme, reduces the content of angiotensin II, causes systemic vasodilation, and causes blood pressure reduction. This product has a significant antihypertensive effect on rat models of type II renal hypertension, type I renal hypertension, and essential hypertension.

Ingredients

The main ingredient of this product is: Enalapril Maleate.

Name Description Content CAS NO. Manufacturer
Enalapril maleateIngredients

This product is an angiotensin converting enzyme inhibitor. After oral administration, it is hydrolyzed into enalaprilat in the body, which strongly inhibits angiotensin converting enzyme, reduces the content of angiotensin II, causes systemic vasodilation, and causes blood pressure reduction. This product has a significant antihypertensive effect on rat models of type II renal hypertension, type I renal hypertension, and essential hypertension.

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76095-16-4 35

Appearance

This product is a hard capsule, and the contents are white or off-white powder and granules.

Indication

Used to treat essential hypertension.

Usage and Dosage

Oral. The initial dose is 5mg-10mg per day, divided into 1-2 doses. For patients with severe renal impairment (creatinine clearance rate less than 30ml/min), the dose is 2.5mg per day. The dose can be gradually increased according to blood pressure levels. The general effective dose is 10-20mg per day, and the maximum daily dose should not exceed 40mg. It can be used in combination with other antihypertensive drugs, especially diuretics, to significantly enhance the antihypertensive effect, but it should not be used in combination with potassium-retaining diuretics.

Adverse Reactions

Symptoms may include dizziness, headache, drowsiness, dry mouth, fatigue, upper abdominal discomfort, nausea, chest tightness, cough, proteinuria, rash, flushing, etc. If necessary, reduce the dosage. If leukopenia occurs, stop taking the drug.

Precautions

Patients who are allergic to this product or have bilateral renal artery stenosis should not use this product. Children and patients with severe renal impairment should use it with caution.

Special Population Medication

Precautions for children: Use with caution in children Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women Precautions for the elderly: This experiment has not been conducted and there is no reliable reference literature.

Drug Interactions

Not yet clear.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

5mg

Validity Period

24 months

Manufacturer

Zhejiang YIXIN Pharmaceutical Co., Ltd.

  • Founded in:

    1993-01-20
  • Address:

    No. 5-1, Zhiyuan Road, Shanghua Street, Lanxi City, Zhejiang Province
  • Tax NO.:

    91330000147380685J
  • Registered Funds:

    40.1716 million yuan
  • Website:

  • Email:

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