On ECHEMI
Home > Drugs > Polyethylene glycol 4000 powder

Polyethylene glycol 4000 powder

Function and Efficacy

This product is not absorbed after oral administration, and forms a hypertonic solution in the intestine, which prevents the intestine from absorbing water and retains the water in the colon cavity. It can soften the feces through local osmotic action, increase the volume and weight of the feces to normal, and then produce smooth defecation. Patients usually restore normal defecation frequency within 24 to 48 hours after taking the medicine, and gradually establish a defecation pattern close to nature and normal. This product is not absorbed after oral administration and has very low toxicity. Literature reports that the LD50 of this product for oral administration in mice is 50g/kg. While treating constipation, polyethylene glycol 4000 does not change the physiological environment of the intestine, does not affect the intestinal absorption of water, electrolytes and nutrients, does not affect the normal intestinal flora, does not produce gas after taking it, and does not affect the heart, liver, and kidney functions. Therefore, it can be prescribed to special and high-risk groups, such as pregnant women, the elderly, diabetics, patients with hypertension and poor heart function, etc.

Ingredients

The main ingredients of this product are: polyethylene glycol 4000, which is a mixture formed by the condensation of ethylene oxide and water.

Appearance

This product is white or off-white powder.

Indication

Symptomatic treatment of constipation in adults.

Usage and Dosage

Oral administration: Dissolve the powder in a large glass of water. Take 1 to 2 bags per day.

Adverse Reactions

If the dosage of this product is too large, diarrhea or mild discomfort may occur, which can be relieved after 24 to 48 hours after stopping the drug, but the dosage can be reduced to continue treatment. Symptoms of abdominal pain (stomach pain) may also occur during medication.

Precautions

1. It is contraindicated for patients with certain small intestine or colon diseases such as intestinal obstruction, intestinal perforation, gastric retention, gastrointestinal bleeding, toxic enteritis, toxic megacolon or intestinal volvulus; 2. It is contraindicated for patients with abdominal pain (stomach pain).

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

Since taking this product may shorten the residence time of other oral drugs in the digestive tract and interfere with drug absorption, a longer interval (at least 2 hours) should be taken between taking this product and other drugs. To avoid interactions between several drugs, please systematically inform your doctor or pharmacist of any treatments taken at the same time.

Storage

Sealed, store in a dry place.

Packaging Specification

10g

Validity Period

36 months

Manufacturer

Haikou Pharmaceutical Factory Co., Ltd.

  • Founded in:

    1990-03-09
  • Address:

    No. 192, Nanhai Avenue, Xiuying District, Haikou City, Hainan Province
  • Tax NO.:

    91460100984090386D
  • Registered Funds:

    562.352031 yuan
  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.