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Levofloxacin Lactate Eye Drops

Function and Efficacy

Levofloxacin is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial topoisomerase IV and DNA gyrase (both type II topoisomerases) and hinder the replication of bacterial DNA to achieve antibacterial effects. Levofloxacin has the characteristics of a broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Citrobacter, Acinetobacter, and Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, and Neisseria gonorrhoeae. It also has good antibacterial effects on some methicillin-sensitive Staphylococci, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococci, and Legionella, Mycoplasma, and Chlamydia, but has poor effects on anaerobic bacteria and enterococci.

Ingredients

Levofloxacin lactate.

Name Description Content CAS NO. Manufacturer
LEVOFLOXACIN LACTATEIngredients

It achieves antibacterial effect by inhibiting the activity of bacterial topoisomerase IV and DNA gyrase, hindering the replication of bacterial DNA. It has good antibacterial effect on most Enterobacteriaceae, Gram-negative bacteria, some Gram-positive bacteria, Legionella, Mycoplasma, Chlamydia, but has poor effect on anaerobic bacteria and enterococci.

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294662-18-3 11

Appearance

This product is a light yellow-green clear liquid.

Indication

It is suitable for the treatment of external eye infections such as bacterial conjunctivitis, keratitis, corneal ulcers, and dacryocystitis.

Usage and Dosage

Place 1 to 2 drops into the eyelids, 3 to 5 times a day, or as directed by your doctor.

Adverse Reactions

Occasionally there is a mild stinging sensation.

Precautions

It is contraindicated for patients who are allergic to this product or quinolones.

Special Population Medication

Precautions for children: When this type of drug is used systemically, it can cause joint damage in small animals, but there is currently no evidence that the use of lactated levofloxacin eye drops will have any effect on the development of children's bones and joints. And the amount of this drug that enters the body when using this product is much less than the amount ingested when it is used systemically. It is recommended to use it after consulting a clinician. Precautions for pregnancy and lactation: This type of drug is prohibited when used systemically. Although the amount of this drug that enters the body due to the use of this product is much less than the amount ingested when it is used systemically (orally, by injection), it is better than no research data on whether pregnant and lactating women will cause systemic toxic reactions due to local use of the drug. It is recommended to use it only when the benefits of using this drug for treatment are greater than the possible adverse consequences. Precautions for the elderly: No differences in the efficacy and safety of this product have been observed between elderly patients and other adult patients after using it.

Drug Interactions

1. Pharmacological action: Levofloxacin is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial topoisomerase IV and DNA gyrase (both are type II topoisomerases), hindering the replication of bacterial DNA and achieving antibacterial effect. Levofloxacin has the characteristics of a broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, as well as Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, and Neisseria gonorrhoeae. It has strong antibacterial activity against some methicillin-sensitive Staphylococci, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococci, and Legionella.

Storage

Keep away from light, tightly closed, in a cool place.

Packaging Specification

5ml:15mg (based on C18H20FN3O4)

Validity Period

36 months

Manufacturer

Hangzhou Guoguang Pharmaceutical Co., Ltd.

  • Founded in:

    2000-03-22
  • Address:

    No. 258, No. 12 Street, Hangzhou Economic and Technological Development Zone, Zhejiang Province
  • Tax NO.:

    91330100720055560A
  • Registered Funds:

    75.5 million yuan
  • Website:

  • Email:

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