Metronidazole Furazolidone Suppositories
Function and Efficacy
Frankincense in this product has the effects of promoting blood circulation, relieving pain, removing decay and promoting tissue regeneration; alum has the effects of detoxification and killing insects, drying dampness and stopping sores, stopping bleeding and removing decay; borneol has the effects of clearing away heat and inflammation, dispersing knots and relieving pain, and removing swelling and removing cataracts. Furazolidone has a therapeutic effect on vaginal infections caused by Trichomonas; metronidazole has the effect of killing Trichomonas. It has a killing effect on anaerobic microorganisms. The metabolites generated when it is reduced in the human body also have an anti-anaerobic effect, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately leading to bacterial death. The results of the long-term toxicity test on rats showed that after observing general behavioral signs, no abnormal behavioral signs were observed in each dose group, each time, and each test case, and the animals gained weight rapidly and developed well. There were no significant differences in the various indicators tested in the blood routine, liver function, and kidney function tests, all of which were within the physiological value range. Systematic autopsy and organ coefficient calculation showed no visible pathological changes in each group. There was no significant difference in organ coefficients between groups, all of which were within the physiological range. Morphological examination of the main organs showed no abnormal tissue morphology in each test group. No abnormal changes were observed in the 3-week recovery observation. This indicates that this product does not cause delayed toxicity and side effects in rats with long-term poisoning. This product was administered vaginally to rats. 24 hours, 48 hours and 7 days after administration, local vaginal anatomical observation and pathological examination showed no edema, exudation, congestion, inflammatory cell infiltration, congestion, ulceration, and no abnormal reactions were observed in the whole body. This indicates that this product does not cause irritation and pathological damage to the vagina, and has no adverse effects on the whole body.
Ingredients
Alum, frankincense, borneol, furazolidone, metronidazole.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Aluminium potassium sulfate dodecahydrateIngredients |
Detoxification, insecticide, dampness-drying, sore-hemostasis, and rot-removing More |
7784-24-9 | 3 | |
| OLIBANUM GUMIngredients |
Activate blood circulation, relieve pain, eliminate rot, promote tissue regeneration More |
8050-07-5 | 0 | |
| BorneolIngredients |
Clears away heat and relieves inflammation, relieves stagnation and relieves pain, reduces swelling and removes cataracts More |
507-70-0 | 1 | |
| FurazolidoneIngredients |
It has a therapeutic effect on vaginal infections caused by Trichomonas More |
67-45-8 | 12 |
Appearance
This product is a suppository.
Indication
It is used for cervicitis, cervical erosion, trichomonas vaginitis, bacterial vaginitis, fungal vaginitis. It can also be used for pelvic inflammatory disease and adnexitis.
Usage and Dosage
Vaginal medication. Take 1 pill at a time, every other day. Use disposable gloves to insert the suppository into the posterior fornix of the vagina, and take the medication before going to bed. Take the medication after menstruation, 5 times as a course of treatment.
Adverse Reactions
Furazolidone and metronidazole in this product often cause gastrointestinal reactions such as nausea and vomiting, allergic reactions (mostly urticaria), drug fever, and asthma. It may also cause pulmonary infiltration, headache, orthostatic hypotension, hypoglycemia, etc.
Precautions
1. It is contraindicated for patients with active central nervous system diseases and blood diseases. 2. It is contraindicated for patients who are allergic to this product. 3. It is contraindicated for patients during menstruation or vaginal bleeding.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Elderly patients should use with caution due to decreased liver function.
Drug Interactions
Furazolidone and metronidazole in this product may interact with the following drugs. 1. It can inhibit the metabolism of warfarin and other oral anticoagulants, enhance their effects, and cause the prothrombin time to be prolonged. 2. The simultaneous use of drugs that induce liver microsomal enzymes such as phenytoin sodium and phenobarbital can enhance the metabolism of this product, reduce the blood drug concentration, and slow down the excretion of phenytoin sodium. 3. The simultaneous use of drugs that inhibit the activity of liver microsomal enzymes such as cimetidine can slow down the metabolism and excretion of this product in the liver, prolong the serum half-life of this product, and the dosage should be adjusted according to the results of blood drug concentration determination. 4. This product interferes with the metabolism of disulfiram. Patients who use the two together may experience mental symptoms after drinking. Therefore, patients who have used disulfiram within 2 weeks should not use this product again. 5. It can interfere with the results of aminotransferase and LDH determinations, and can reduce cholesterol and triglyceride levels.
Storage
Keep away from light, tightly closed, in a cool and dry place.
Packaging Specification
Compound
Validity Period
24 months
Manufacturer
Jinzhou Jiutai Pharmaceutical Co., Ltd.
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Founded in:
1998-09-02 -
Address:
No. 41, Tai'anli, Taihe District, Jinzhou City, Liaoning Province -
Tax NO.:
91210700242034190P -
Registered Funds:
40.986462 million yuan -
Website:
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Email: