It inhibits the transmembrane calcium ion influx between the myocardium and vascular smooth muscle without changing the blood calcium concentration, selectively dilates the coronary vascular smooth muscle, reduces peripheral vascular resistance, reduces myocardial oxygen consumption and total peripheral resistance, and increases coronary collateral circulation and coronary blood flow.

This product is an intermediate in the synthesis of Schisandrae Chinensis A, which can reduce liver damage and alanine aminotransferase (ALT) elevation caused by carbon tetrachloride; inhibit liver microsomal lipid peroxidation caused by carbon tetrachloride, carbon tetrachloride metabolism into carbon monoxide, and reduce the consumption of reduced coenzyme II and oxygen, protecting the structure and function of liver cell biomembrane; reduce prednisone-induced liver ALT elevation, promote liver regeneration in mice with partial hepatectomy; have a significant induction effect on cytochrome P450 enzyme activity, enhance the detoxification ability of carbon tetrachloride and certain carcinogens; improve protein metabolism in some hepatitis patients, increase albumin and reduce globulin. It has no negative conversion effect on HbsAg and HbeAg, and cannot shrink enlarged liver and spleen.

Unspecified

This product belongs to the macrolide antibiotics. It has antibacterial activity against Staphylococcus (except methicillin-resistant strains), various groups of streptococci and Gram-positive bacilli. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. are also sensitive to this product. This product also has antibacterial effects on various anaerobic bacteria except Bacteroides fragilis and Fusobacterium. It also has inhibitory effects on Legionella, Campylobacter fetus, certain spirochetes, Mycoplasma pneumoniae, Rickettsia and Chlamydia. This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site ("P" site), blocking the transfer RNA (t-RNA) from binding to the "P" site, and also blocking the displacement of the polypeptide chain from the acceptor site ("A" site) to the "P" site, thereby inhibiting bacterial protein synthesis.