Tiapride Hydrochloride Injection

This product is a neuropsychiatric tranquilizer, which has a blocking effect on the hyperactivity of dopaminergic D2 receptors in the midbrain limbic system. Experiments have shown that this product has the effects of combating movement disorders, analgesia, antianxiety and neuropsychiatric symptoms caused by alcohol poisoning. The intramuscular injection LD50 of this product for mice is 891mg/kg, and the intravenous injection LD50 is 179mg/kg.

The main ingredient of this product is siopride hydrochloride. Chemical name: N-(2-ethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide hydrochloride. Chemical structure: Molecular formula: C15H24N2O4S·HCl Molecular weight: 364.89 Auxiliary material: sodium chloride.

This product is a colorless clear liquid.

It is used for neuropsychiatric disorders caused by chronic alcohol poisoning, as well as chorea, Tourette syndrome and senile psychosis. It can also be used for various pains such as intractable headaches, painful cramps, sciatica, joint pain and acute alcohol poisoning.

Intravenous injection or intravenous drip after dilution with 5% glucose or normal saline, 1-2 vials at a time, 2-6 vials per day. The dosage should be increased gradually from a small dose. Intravenous injection should be slow.

Adverse reactions are mild, including drowsiness, dry mouth, dizziness, fatigue, constipation, etc. Extrapyramidal side effects such as tremor and akathisia are occasionally seen, and temporary amenorrhea and galactorrhea are rare. Generally, they can disappear on their own by stopping the drug or reducing the dosage. Some patients who are highly sensitive to this product may have severe extrapyramidal side effects, which can be quickly relieved by anticholinergic drugs such as scopolamine when necessary.

Pheochromocytoma, unstable epilepsy.

Precautions for children: Reduce the dosage for children, or follow the doctor's advice. Precautions for pregnancy and lactation: Animal experiments have not proven teratogenic effects. Due to the lack of clinical data, there is no data report on the effects on the fetus during pregnancy. Due to the long-term use of siopride hydrochloride by mothers, there are occasional reports of extrapyramidal side effects in newborns. Pregnant and lactating women are not recommended to use this product. Precautions for the elderly: Use with caution in the elderly. For patients with severe cardiovascular diseases, hypotension may occur due to changes in hemodynamics. It is recommended to start with a small dose.

It has synergistic effects with hypnotics and central nervous system depressants and needs to be used in reduced dosage.

Keep away from light and store in a sealed container.

2ml: 100mg

36 months

Jiangsu Lianshui Pharmaceutical Co., Ltd.

• Founded in:

  1999-05-21

• Address:

  No. 18, Hongri Avenue, Lianshui Economic Development Zone

• Tax NO.:

  91320826139830519D

• Registered Funds:

  80 million yuan

• Email:

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