Lomustine Capsules
Ingredients
The main ingredient of this product: Lomustine. Chemical name: 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea Molecular weight: C10H18ClN3O2
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| LomustineIngredients |
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea More |
13010-47-4 | 4 |
Appearance
This product is in the form of capsules.
Usage and Dosage
100-130 mg/m2, taken all at once, once every 6-8 weeks, 3 times as a course of treatment.
Adverse Reactions
Nausea and vomiting may occur within 6 hours after oral administration and may last for 2 to 3 days. Pre-treatment with sedatives or metoclopramide and taking the drug on an empty stomach can alleviate the symptoms. A small number of patients experience gastrointestinal bleeding and liver damage. Bone marrow suppression: thrombocytopenia can be seen 3 to 5 weeks after taking the drug. White blood cell reduction can occur twice, in the first and fourth weeks after taking the drug, and will not recover until the sixth to eighth week. However, bone marrow suppression is cumulative. Occasionally, systemic rash is seen, which may cause teratogenesis and may also suppress testicular or ovarian function, causing amenorrhea or azoospermia.
Precautions
Patients with liver damage, white blood cell count less than 4×109/L, and platelet count less than 80×109/L are contraindicated. In case of concurrent infection, the infection should be treated first.
Special Population Medication
Precautions for children: 100-130mg/m2, taken at once, repeated every 6-8 weeks. Precautions for pregnancy and lactation: This drug has carcinogenic and teratogenic effects, so it is contraindicated for pregnant and lactating women. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference literature.
Drug Interactions
When this product is used in combination chemotherapy, anticancer drugs that can severely reduce leukocytes and platelets should be avoided.
Storage
Keep in a light-proof and airtight container.
Packaging Specification
6s
Validity Period
24 months
Manufacturer
ZHONGFU Pharmaceutical Co., Ltd.
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Founded in:
2000-04-22 -
Address:
No. 2709, Yuwang North Street, Hanting District, Weifang City, Shandong Province -
Tax NO.:
913707037232674976 -
Registered Funds:
78.364 million yuan -
Website:
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Email: