Dexibuprofen Capsules
Function and Efficacy
Dextrorotatory ibuprofen is the active ingredient of ibuprofen. It exhibits anti-inflammatory, analgesic and antipyretic effects by inhibiting the synthesis of prostaglandins or other inflammatory mediators. It has a stronger effect than ibuprofen and takes effect quickly.
Ingredients
The main ingredient of this product is dexibuprofen.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| (S)-(+)-IbuprofenIngredients |
By inhibiting the synthesis of prostaglandins or other inflammatory mediators, it exhibits anti-inflammatory, analgesic and antipyretic effects. It is more potent than ibuprofen and takes effect more quickly. More |
51146-56-6 | 21 |
Appearance
This product is a hard capsule, and the contents are white or off-white granules.
Indication
1. Relieve acute attacks or persistent joint swelling and pain in various chronic arthritis such as rheumatoid arthritis, osteoarthritis, spondyloarthropathies, gouty arthritis, rheumatic arthritis, etc., without the role of etiology treatment and control of the course of the disease; 2. Treat various non-articular soft tissue rheumatic pains, such as shoulder pain, tenosynovitis, bursitis, myalgia and pain caused by sports injuries; 3. Acute mild and moderate pain such as post-surgery, post-traumatic, post-aging, primary dysmenorrhea, toothache, headache, etc.; 4. It has an antipyretic effect on fever in adults and children.
Usage and Dosage
Oral. For rheumatism, 2 capsules at a time, 3-4 times a day; for pain relief of mild or moderate pain and dysmenorrhea, 1 capsule at a time, 3-4 times a day; for children over 6 years old, the daily dose should not exceed 2 capsules, or follow the doctor's advice.
Adverse Reactions
1. Gastrointestinal symptoms include indigestion, stomach burning, stomach pain, nausea, and vomiting, which occur in 16% of long-term users; the above symptoms disappear when the drug is discontinued, and most of the patients who do not stop the drug can tolerate it. A few (≦1%) develop gastric ulcers and gastrointestinal bleeding, and some suffer from ulcer perforation. 2. Neurological symptoms such as headache, drowsiness, dizziness, and tinnitus are rare, occurring in 1%-3% of patients. 3. Renal insufficiency is rare, mostly occurring in patients with potential renal disease; but a small number of users may experience lower limb edema. 4. Other rare symptoms include rash, bronchial asthma attacks, elevated liver enzymes, leukopenia, etc. 5. If gastrointestinal bleeding, liver and kidney damage, visual impairment, abnormal blood counts, and allergic reactions occur during medication, the drug should be discontinued.
Precautions
1. Patients who are known to be allergic to this product. 2. Patients who have asthma, urticaria or allergic reactions after taking aspirin or other non-steroidal anti-inflammatory drugs. 3. Contraindicated for the treatment of perioperative pain during coronary artery bypass grafting (CABG). 4. Patients with a history of gastrointestinal bleeding or perforation after taking non-steroidal anti-inflammatory drugs. 5. Patients with active peptic ulcers/bleeding, or patients with recurrent ulcers/bleeding in the past. 6. Patients with severe heart failure.
Special Population Medication
Precautions for children: Not clear. Precautions for pregnancy and lactation: Contraindicated for pregnant and lactating women. Precautions for the elderly: Elderly patients are prone to adverse reactions due to decreased liver and kidney function, so they should be used with caution or in a reduced dosage.
Drug Interactions
1. When used with other non-steroidal anti-inflammatory drugs, it increases gastrointestinal side effects and has the risk of causing ulcers. Long-term use with acetaminophen may increase toxic side effects on the kidneys. 2. When used with aspirin or other salicylic acid drugs, the efficacy is not enhanced, but the incidence of gastrointestinal adverse reactions and bleeding tendency increases. 3. When used with anticoagulants such as heparin and dicoumarol and platelet aggregation inhibitors, there is an increased risk of bleeding. 4. When used with furosemide, the latter's sodium excretion and antihypertensive effects are weakened. 5. When used with verapamil and nifedipine, the blood concentration of this product increases. 6. This product can increase the blood concentration of digoxin. When used together, it is necessary to pay attention to adjusting the dose of digoxin. 7. This product can enhance the effect of antidiabetic drugs (including oral hypoglycemic drugs). 8. This product can affect when used with antihypertensive drugs
Storage
seal.
Packaging Specification
0.15g
Validity Period
24 months
Manufacturer
Suzhou NO.4 Pharmaceutical FACTORY Co., Ltd.
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Founded in:
1981-12-14 -
Address:
No. 2, Haixin Road, Haiyu Town, Changshu City, Jiangsu Province -
Tax NO.:
91320581137714223E -
Registered Funds:
129 million yuan -
Website:
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Email: