Doxycycline Hydrochloride Enteric-coated Capsules

Tetracycline antibiotics. This product is a broad-spectrum antibacterial agent with bactericidal effects at high concentrations. Rickettsia, Mycoplasma, Chlamydia, atypical mycobacteria, and spirochetes are also sensitive to this product. This product is more effective against Gram-positive bacteria than Gram-negative bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, and Yersinia are sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant Neisseria gonorrhoeae is also resistant to doxycycline. Due to the widespread use of tetracyclines over the years, common clinical pathogens have become seriously resistant to this product, including Gram-positive bacteria such as Staphylococcus and most Gram-negative bacilli. This product is different from different varieties of tetracycline antibiotics.

Doxycycline hydrochloride

This product is a hard capsule, and the contents are light yellow to yellow pellets.

1. This product can be used as one of the selected drugs for the following diseases. Rickettsial diseases, such as epidemic typhus, endemic typhus, Rocky Mountain fever, scrub typhus and Q fever. Mycoplasma infection. Chlamydia infection, including psittacosis, venereal disease, lymphoedema, nonspecific urethritis, salpingitis, cervicitis and trachoma. Relapsing fever. Brucellosis. Cholera. Tularemia. Plague. Chancroid. It needs to be used in combination with aminoglycosides to treat brucellosis and plague. 2. Due to the serious resistance of common pathogens to tetracyclines, this product is only indicated when the pathogens are sensitive to it. Most Staphylococci are resistant to this product. 3. This product can be used for tetanus, gas gangrene, yaws, syphilis, gonorrhea and leptospirosis in patients allergic to penicillins, as well as Actinomycetes and Listeria infections. 4. It can be used as an auxiliary treatment for patients with moderate to severe acne.

Antibacterial and antiparasitic infections: Adults, 100 mg on the first day, once every 12 hours, followed by 100-200 mg once a day, or 50-100 mg once every 12 hours. Gonorrheal Neisseria urethritis and cervicitis: 100 mg once every 12 hours for 7 days. Non-gonococcal Neisseria urethritis caused by Chlamydia trachomatis, and simple urethritis, cervicitis or rectal infection caused by Chlamydia trachomatis: 100 mg once, twice a day, for at least 7 days. Syphilis: 150 mg once every 12 hours, for at least 10 days. Children over 8 years old: 2.2 mg/kg of body weight once every 12 hours on the first day, followed by 2.2-4.4 mg/kg of body weight once a day, or 50-100 mg once every 12 hours.

1. Digestive system: Oral administration of this product may cause gastrointestinal reactions such as nausea, vomiting, abdominal pain, and diarrhea. There have been occasional reports of esophagitis and esophageal ulcers, which mostly occur in patients who are bedridden immediately after taking the drug. 2. Hepatotoxicity: It is more likely to occur in patients with fatty liver degeneration and pregnant women, and it may also occur in patients without the above conditions. Pancreatitis may occasionally occur, and the pancreatitis caused by this product may also occur simultaneously with hepatotoxicity, and the patient does not have primary liver disease. 3. Allergic reactions: Mostly maculopapular rash and erythema, a small number of patients may have urticaria, angioedema, allergic purpura, pericarditis, and worsening of skin lesions of systemic lupus erythematosus, and exfoliative dermatitis is not common. Occasionally, anaphylactic shock and asthma occur. Some patients who use this product

Patients with a history of allergy to tetracyclines are contraindicated.

Precautions for children: Children under 8 years old are prohibited to use. Precautions for pregnancy and lactation: This product can enter the fetus through the placental barrier and deposit in the calcium area of teeth and bones, causing fetal tooth discoloration, poor enamel regeneration and inhibiting fetal bone growth. This type of drug has teratogenic effects in animal experiments, so pregnant women should not take it. This product can be secreted from breast milk, and the concentration in breast milk is relatively high. Lactating women should stop breastfeeding when using it. Precautions for the elderly: This experiment has not been conducted and there are no reliable references.

1. This product can inhibit the activity of plasma prothrombin, so patients receiving anticoagulant therapy need to adjust the dose of anticoagulants. 2. When barbiturates, phenytoin or carbamazepine are used with this product, the above drugs can induce the activity of microsomal enzymes and cause a decrease in the blood concentration of doxycycline, so the dose of doxycycline must be adjusted.

Sealed and stored in a cool and dry place. Validity period: 24 months

0.1g (based on doxycycline)

36 months

TC Pharmaceuticals (Jiangsu) Co., Ltd.

• Founded in:

  1994-12-12

• Address:

  No. 191, Jinyang West Road, Lujia Town, Kunshan City, Jiangsu Province

• Tax NO.:

  91320583608280290E

• Registered Funds:

  126.271311 yuan

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