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Estradiol Benzoate Injection

Function and Efficacy

Estrogen drugs. They can cause endometrial hyperplasia, enhance uterine smooth muscle contraction, and promote breast development and hyperplasia. Large doses inhibit the release of prolactin, counteract the effects of androgens, and increase calcium deposition in bones.

Ingredients

The main ingredient of this product is estradiol benzoate. Its chemical name is: 3-hydroxyestrone-1,3,5 (10)-triene-17beta;-ol-3-benzoate. Its structural formula is: Molecular formula: C25H28O3 Molecular weight: 376.50

Name Description Content CAS NO. Manufacturer
Estradiol benzoateIngredients

Estrogen drugs. They can cause endometrial hyperplasia, enhance uterine smooth muscle contraction, and promote breast development and hyperplasia. Large doses inhibit the release of prolactin, counteract the effects of androgens, and increase calcium deposition in bones.

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50-50-0 9

Appearance

This product is a light yellow clear oily liquid.

Indication

1. Supplementing estrogen deficiency, such as atrophic vaginitis, female gonadal dysfunction, vulvar dryness, menopausal vasomotor symptoms, oophorectomy, primary ovarian failure, etc.; 2. Advanced prostate cancer (contraindicated for patients with breast cancer and ovarian cancer); 3. Combined with progesterone drugs, it can inhibit ovulation; 4. Amenorrhea, abnormal menstruation, functional uterine bleeding, and uterine hypoplasia.

Usage and Dosage

1 For menopausal syndrome, 1-2 mg intramuscularly once, 2-3 times a week. 2 Uterine hypoplasia, 1-2 mg once, intramuscularly once every 2-3 days. 3 Functional uterine bleeding, 1 mg-2 mg intramuscularly daily, reduce the dose as appropriate after the bleeding is clear, and withdraw with progesterone at a later date. 4 Weaning, 2 mg intramuscularly daily, reduce the dose after no more than 3 days or change to a small amount of oral medication until it takes effect.

Adverse Reactions

There may be nausea, headache, breast tenderness, and occasionally thrombosis, rash, water and sodium retention, etc.

Precautions

1. It is contraindicated for patients with thrombophlebitis, pulmonary embolism, liver and kidney diseases, and estrogen-related tumors. 2. It is contraindicated for pregnant and lactating women.

Special Population Medication

Precautions for children: It may cause premature puberty and should not be used. Precautions for pregnancy and lactation: It is forbidden for pregnant and lactating women. Precautions for the elderly: It is not clear yet.

Drug Interactions

When used in combination with hypoglycemic drugs, their hypoglycemic effect may be weakened and the dosage should be adjusted.

Storage

Keep away from light and store in sealed container.

Packaging Specification

1ml:2mg

Validity Period

48 months

Manufacturer

Shanghai CP GENERAL Pharmaceutical Co., Ltd.

  • Founded in:

    2000-11-20
  • Address:

    No. 889, Shennan Road, Minhang District, Shanghai
  • Tax NO.:

    913100007030684906
  • Registered Funds:

    107.37 million yuan
  • Website:

  • Email:

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