Azelaic acid cream

Pharmacological action: The exact mechanism of action of this product is not yet clear. In vitro, azelaic acid has antibacterial activity against Propionibacterium acnes and Staphylococcus epidermidis, and the principle may be to inhibit the protein synthesis of microorganisms. This product can return the keratinization process of the hair follicle infundibulum to normal. After electron microscopy and immunohistochemistry studies on the skin specimens of the subjects, it was also found that after treatment, the skin stratum corneum became thinner, the keratinocyte clear protein particles decreased and became smaller, and the content and distribution of filaggrin (a component of keratinocyte clear protein) in the epidermis decreased. These changes may be related to the drug's inhibition of acne formation. Toxicological studies: Genetic toxicity Ames test, Chinese hamster ovary cell and lymphocyte mutagenesis test, mouse dominant dapoxetine test, genotoxicity test, and toxicity test.

The main ingredient of this product is azelaic acid, and its chemical name is 1,9-zelaic acid.

This product is a white ointment with an emulsion base.

This product is suitable for the local treatment of mild to moderate inflammatory acne vulgaris.

For external use. After washing and drying the skin, apply this product in a thin layer on the acne twice a day, once in the morning and once in the evening. Apply vigorously to make sure it penetrates deeply into the skin. Wash hands after application.

Adverse reactions are generally mild and short-lived. 1-5% of patients experience itching, burning, irritation and stinging at the beginning of medication. Other adverse reactions include erythema, dry skin, rash, desquamation, irritation, dermatitis and contact dermatitis, with a total incidence of less than 1%. This product has the potential to cause allergic reactions. Very few reports have stated that the use of this product has caused worsening of asthma, decreased skin pigmentation, white spots, hirsutism, redness (a sign of follicular keratosis pilaris) and recurrent exacerbation of herpes on the lips.

It is contraindicated for those who are allergic to any ingredient in this product.

If you are using other medicines, you should consult your physician or pharmacist before using this product.

Keep tightly closed in a cool place.

30g:6g

Zhejiang Conba Pharmaceutical Co., Ltd.

• Founded in:

  1993-01-09

• Address:

  No. 1 Kangenbei Avenue, Lanxi City, Zhejiang Province

• Tax NO.:

  91330000142924161N

• Registered Funds:

  2570.037319 yuan

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