Racecadotril Granules

Racecadotril is an enkephalinase inhibitor. Enkephalinase can degrade enkephalins. This product can selectively and reversibly inhibit enkephalinase, thereby protecting endogenous enkephalins from degradation, prolonging the physiological activity of endogenous enkephalins in the digestive tract, and reducing excessive secretion of water and electrolytes. Oral racecadotril acts on peripheral enkephalinase, does not affect the enkephalinase activity of the central nervous system, and has no significant effect on gastrointestinal motility and intestinal basal secretion.

Main ingredient: Racecadotril, chemical name: (±) N-((acetylmercapto-2-methyl)-1-oxo-3-phenylpropyl) glycine benzyl ester

This product is white or off-white granules with aromatic odor and slightly sweet taste.

Used for acute diarrhea in infants and children over 1 month old, combined with oral rehydration or intravenous rehydration when necessary.

Oral administration, three times a day, 1.5 mg per kg of body weight each time; the total daily dose should not exceed 6 mg per kg of body weight. Continuous use should not exceed 7 days. If necessary, oral rehydration or intravenous rehydration should be used in combination. Recommended dose: 1 Infant dosage: 1 to 9 months old (weight < 9kg), 10 mg (1 bag) each time, three times a day; 9 to 30 months old (weight 9 to 13kg), 20 mg (2 bags) each time, three times a day. 2 Children's dosage: 30 months to 9 years old (13kg~27kg), 30 mg (1 bag) each time, three times a day; 9 years old and above (weight > 27kg), 60 mg (2 bags) each time, three times a day.

Occasionally, drowsiness, rash, constipation, nausea and abdominal pain may occur.

It is contraindicated for patients with impaired liver and kidney function; patients who cannot ingest fructose, have poor absorption of glucose or galactose, lack sucrase or maltase; patients who are allergic to racecadotril.

Precautions for children: See Dosage and Administration. Precautions for pregnancy and lactation: No such experiment has been conducted and no reliable references are available. Precautions for the elderly: No such experiment has been conducted and no reliable references are available.

1. Cytochrome P450-3A4 inhibitors such as erythromycin and ketoconazole may reduce the metabolism of racecadotril and increase its toxicity; 2. Cytochrome P450-3A4 inducers such as rifampicin may reduce the anti-diarrhea effect of racecadotril.

Keep sealed.

30mg

Tentatively 24 months.

Sichuan Baili Pharmaceutical Co., Ltd.

• Founded in:

  1996-08-23

• Address:

  Chengdu Cross-Strait Science and Technology Industrial Development Park, Wenjiang District, Chengdu

• Tax NO.:

  915101157377026059

• Registered Funds:

  125 million yuan

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