Promethazine Bile Tablets

Animal experiments have shown that hyodeoxycholic acid in pig bile powder has a significant expectorant effect and a significant antipyretic effect on experimental guinea pigs after fever. Pharmacological animal experiments using pig bile have shown that it has an anticonvulsant effect and a synergistic effect with barbiturates. Promethazine hydrochloride is a phenothiazine derivative that competes with histamine released from tissues for H1 receptors, antagonizes the contraction or contracture of histamine on the gastrointestinal tract, trachea, bronchi or bronchiolar smooth muscle, and relieves the spasmodic and congestive effects of histamine on bronchial smooth muscle. The antiemetic effect of promethazine hydrochloride may be related to the inhibition of the emetic chemoreceptor area of the medulla oblongata. The mechanism of inhibition of the central nervous system has not yet been clearly elucidated, but it may be due to an indirect reduction in the excitability of the brainstem reticular formation activation system.

This product is a compound preparation, and its components are: each tablet contains 62.5 mg of pig bile powder and 6.25 mg of promethazine hydrochloride.

This product is a film-coated tablet, which appears yellow or light yellow after removing the film coating.

Used for cough caused by cold, whooping cough and paroxysmal and spasmodic cough.

Oral administration. Adults: 2 tablets at a time, 3 times a day; 1-5 years old: 1-2 tablets a day; over 6 years old, 2-4 tablets a day, taken in 2 or 3 times. Take after meals and before bedtime.

Less common symptoms include drowsiness, blurred vision or color blindness (mild), dizziness, vertigo, dry mouth, nose and throat, tinnitus, rash, stomach pain or stomach discomfort, slow reaction (more common in children), nausea or vomiting, and even jaundice.

1. It is contraindicated for those who are allergic to phenothiazines. 2. It is contraindicated for those with severe liver dysfunction and jaundice caused by gallstones. 3. It is contraindicated for pregnant women 2 weeks before delivery. 4. It is contraindicated for children under 3 months old.

Precautions for children: Insufficient drug metabolizing enzymes in children under 3 months old may cause renal insufficiency. It should be prohibited. Precautions for pregnancy and lactation: 1. This product is prescribed with promethazine hydrochloride. Pregnant women taking this drug may induce jaundice and extrapyramidal symptoms in infants. Therefore, pregnant women should stop using this drug 1-2 weeks before delivery. 2. General antihistamines are more dangerous to infants, especially newborns and premature infants. Breastfeeding women must weigh the pros and cons when using this product. Precautions for the elderly: Elderly people are prone to dizziness and hypotension when taking large doses of this drug.

1. Alcohol or other central nervous system depressants, especially anesthetics, barbiturates, monoamine oxidase inhibitors or tricyclic antidepressants, when taken together with this product, can enhance the effects of promethazine hydrochloride or (and) these drugs. 2. When antihypertensive drugs such as benzylamine, isoquine or guanethidine are used together with this product, the antihypertensive effect of the former is enhanced. 3. When ototoxic drugs such as cisplatin, paromomycin and other aminoglycoside antibiotics, salicylic acid preparations and vancomycin are used together with this product, their ototoxic symptoms can be masked.

Keep away from light and store in sealed container.

Pig bile powder 62.5 mg, promethazine hydrochloride 6.25 mg

24 months

Liaoyuan Yulongyadong Pharmaceutical Co., Ltd.

• Founded in:

  1999-08-03

• Address:

  No. 5 Yiyang, Youyi Road, Longshan District, Liaoyuan City (South side of Yijian Road Crossing)

• Tax NO.:

  912204007171163934

• Registered Funds:

  17.303 million yuan

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