Magnesium valproate tablets

The anti-epileptic effect may be related to the competitive inhibition of gamma-aminobutyric acid transferase, which reduces its metabolism and increases the content of gamma-aminobutyric acid in the brain. It has different degrees of antagonism against convulsions caused by various factors.

Magnesium valproate.

This product is white tablets or sugar-coated tablets. Sugar-coated tablets appear white after removing the sugar coating.

It is used to treat various types of epilepsy. It can also be used to treat manic episodes of bipolar disorder.

For oral anti-epileptic, start with a low dose, 200 mg once, 2 to 3 times a day, gradually increase to 300 to 400 mg once, 2 to 3 times a day. For anti-mania, start with a low dose, 200 mg once, 2 to 3 times a day, gradually increase to 300 to 400 mg once, 2 to 3 times a day. The maximum dose does not exceed 1.6g per day. Children over 6 years old should take 20 to 30 mg/kg per day according to their body weight, divided into 3 to 4 doses.

Common symptoms include nausea, vomiting, loss of appetite, diarrhea, etc. A few may experience lethargy, tremor, ataxia, hair loss, abnormal excitement and irritability, etc. Occasionally, allergic rash, thrombocytopenia or platelet aggregation inhibition causing abnormal bleeding, leukopenia or toxic liver damage may occur.

It is contraindicated for patients with leukopenia and severe liver disease. It is contraindicated for children under 6 years old. It is contraindicated for pregnant women. This product can be secreted into breast milk. Lactating women should stop breastfeeding while using this product.

Precautions for children: Forbidden for children under 6 years old. Precautions for pregnancy and lactation: Forbidden for pregnant women. This product can be secreted into breast milk, so lactating women should stop breastfeeding while using this product. Precautions for the elderly: Reduce the dosage as appropriate depending on the condition.

1 This product can inhibit the metabolism of phenytoin sodium, phenobarbital, primidone, and ethosuximide, thereby increasing the blood concentration. 2 This product can cause absence epileptic status when used in combination with clonazepam, and should not be used in combination. 3 Antacids can reduce the blood concentration of this product. 4 Aspirin can increase the efficacy and toxic effects of this product. 5 When used in combination with anticoagulants such as warfarin or heparin, and thrombolytic drugs, the risk of bleeding increases. 6 When used in combination with carbamazepine, the induction of liver enzymes can accelerate drug metabolism, which can reduce the blood concentration and half-life of the two. 7 When used in combination with haloperidol and thioxanthenes, phenothiazine antipsychotics, tricyclic antidepressants, and monoamine oxidase inhibitors, it can increase the inhibition of the central nervous system, lower the convulsion threshold and the anticonvulsant effect of valproic acid.

Sealed, store in a dry place.

0.1g

36 months

Hunan Xiangzhong Pharmaceutical Co., Ltd.

• Founded in:

  1998-03-05

• Address:

  No. 18, Daxing South Road, Baoqing Industrial Concentration Zone, Shaoyang City, Hunan Province

• Tax NO.:

  91430500185569358T

• Registered Funds:

  69 million yuan

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