Doxofylline Injection

Doxofylline is a derivative of methylxanthine. It is a bronchodilator that can directly act on the bronchi and relax bronchial smooth muscles. It relaxes smooth muscles by inhibiting phosphodiesterase in smooth muscle cells, thereby suppressing asthma.

Doxofylline. Its chemical name is 1,3-dimethyl-7-(1,3-dioxolan-2-yl)methyl-3,7-dihydro-1H-purine-2,6-dione.

This product is a colorless clear liquid.

Dyspnea caused by bronchial asthma, wheezing chronic bronchitis and other bronchospasms.

Adults take 200 mg each time, once every 12 hours, diluted with 25% glucose injection to 40 ml, slowly injected intravenously, the time should be more than 20 minutes, 5 to 10 days as a course of treatment or follow the doctor's advice. You can also add 300 mg of this product to 100 ml of 5% glucose injection or normal saline injection, slowly drip intravenously, once a day.

The use of xanthine derivatives may cause nausea, vomiting, upper abdominal pain, headache, insomnia, irritability, tachycardia, premature contractions, shortness of breath, hyperglycemia, and proteinuria. Excessive use may also cause severe arrhythmia and paroxysmal spasms. This is an early symptom of poisoning. At this time, the drug should be suspended, and a doctor should be consulted to monitor the blood drug concentration. However, it can still be used after the above signs and symptoms of poisoning have completely disappeared.

Patients with acute myocardial infarction are contraindicated for use in patients who are allergic to doxofylline or xanthine derivatives.

Precautions for children: There is no data on the effectiveness and safety of children. Precautions for pregnancy and lactation: Pregnant and lactating women should avoid use. Precautions for the elderly: The clearance rate of this product may be different in elderly patients, and blood drug concentrations should be monitored.

1 Barbiturates have no significant effect on the metabolism of this product. 2 In animal experiments, macrolides (such as erythromycin) have no significant effect on the metabolism of this product. When used in combination with fluoroquinolones such as enoxacin and ciprofloxacin, the dosage should be reduced.

Keep tightly closed.

10ml:0.1g

24 months.

Zhejiang Beisheng Pharmaceutical Hansheng Pharmaceutical Co., Ltd.

• Founded in:

  2000-01-28

• Address:

  Jiangbei High-tech Industrial Park, Dongyang City, Zhejiang Province

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  913307837176731653

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  80 million yuan

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