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Levodopa tablets

Function and Efficacy

This product is a dopamine-like anti-Parkinson's disease drug. Levodopa is a precursor substance for synthesizing dopamine in the body. It has no pharmacological activity itself. It enters the central nervous system through the blood-brain barrier and is converted into dopamine by dopa decarboxylase to exert its pharmacological effects and improve the symptoms of Parkinson's disease. Since this product can increase neurotransmitters such as dopamine and norepinephrine in the brain, it can also improve the brain's tolerance to ammonia, and is used to treat hepatic coma, improve central nervous system function, make patients sober, and improve symptoms.

Ingredients

The main ingredient of this product is L-dopa, and its chemical name is: 3-hydroxy-L-tyrosine. Its structural formula is: C9H11NO4197.19

Name Description Content CAS NO. Manufacturer
LevodopaIngredients

Dopamine-mimetic anti-Parkinson's disease drugs, as precursors of dopamine synthesis in the body, enter the central nervous system through the blood-brain barrier and are converted into dopamine by dopa decarboxylase, thus improving the symptoms of Parkinson's disease. They can also increase neurotransmitters such as dopamine and norepinephrine in the brain, increase the brain's tolerance to ammonia, and are used to treat hepatic coma, improve central nervous system function, awaken patients, and improve symptoms.

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Appearance

This product is white or off-white tablets.

Indication

For Parkinson's disease and Parkinson's syndrome

Usage and Dosage

Start with 250 mg orally, 2 to 4 times a day, after meals. Depending on the patient's tolerance, increase the dose every 3 to 7 days, ranging from 125 to 750 mg per day, until the best therapeutic effect is achieved. The maximum daily dose is 6 g, divided into 4 to 6 doses. The dose should be reduced for patients with post-encephalitis and the elderly.

Adverse Reactions

Common adverse reactions include: nausea, vomiting, orthostatic hypotension, abnormal involuntary movements of the head, face, tongue, upper limbs and upper body, depression, and dysuria. Less common adverse reactions include: hypertension, arrhythmia, and hemolytic anemia.

Precautions

It is contraindicated for patients with severe mental illness, severe arrhythmia, heart failure, glaucoma, peptic ulcer and a history of convulsions.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: This product can secrete human breast milk, but it can also reduce breast milk secretion; animal experiments show that this product can cause visceral and skeletal deformities. Pregnant and lactating women should not use it. Precautions for the elderly: Not yet clear.

Drug Interactions

1. This product combined with non-selective monoamine oxidase inhibitors can cause acute adrenal crisis. 2. This product combined with papaverine or vitamin B6 can reduce the efficacy of this product. 3. This product combined with acetylspiramycin can significantly reduce the blood concentration of this product and weaken the efficacy. 4. This product combined with reserpine can inhibit the effect of this product and should be avoided. 5. This product combined with antipsychotic drugs should be avoided because the two antagonize each other. 6. This product combined with methyldopa can increase the adverse reactions of this product and enhance the antihypertensive effect of methyldopa.

Storage

Keep in a sealed container

Packaging Specification

250mg

Validity Period

24 months

Manufacturer

Yunnan Phyto Pharmaceutical Co., Ltd.

  • Founded in:

    1998-10-26
  • Address:

    No. 2899, Macheng Road, Majinpu, High-tech Zone, Kunming City, Yunnan Province
  • Tax NO.:

    915300007097131980
  • Registered Funds:

    131.12 million yuan
  • Website:

  • Email:

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