Oxytetracycline Tablets

The main component of this product is: oxytetracycline. Molecular weight: C22H24N2O9

This product is light yellow tablet or sugar-coated tablet.

Oral administration: 6-8 tablets per day for adults, divided into 3-4 times; 30-40 mg/kg per day for children over 8 years old, divided into 3-4 times. This product is contraindicated for children under 8 years old.

1. Digestive system: Gastrointestinal symptoms such as nausea, vomiting, upper abdominal discomfort, abdominal distension, diarrhea, and occasional reports of pancreatitis, esophagitis, and esophageal ulcers, mostly occur in patients who are bedridden immediately after taking the drug. 2. Hepatotoxicity: Usually fatty liver degeneration. Pregnant women and patients with pre-existing renal impairment are prone to hepatotoxicity, but hepatotoxicity can also occur in patients without the above conditions. 3. Allergic reactions: Mostly maculopapular rash and erythema. In addition, urticaria, angioedema, allergic purpura, pericarditis, and exacerbation of systemic lupus erythematosus can be seen. Exfoliative dermatitis is not common. Occasionally, anaphylactic shock and asthma occur. Some patients using tetracycline have photosensitivity when exposed to the sun. Therefore, patients should be advised not to expose themselves directly to sunlight or ultraviolet rays, and to stop taking the drug immediately if erythema appears on the skin. 4. Blood

Patients with a history of allergy to tetracyclines are contraindicated.

Precautions for children: This product can form stable calcium compounds in any bone tissue, leading to yellowing of permanent teeth, poor enamel development and bone growth inhibition, so it is not suitable for children under 8 years old. Precautions for pregnancy and lactation: This product can enter the fetus through the placental barrier and deposit in the calcium area of teeth and bones, causing fetal tooth discoloration, poor enamel regeneration and inhibition of fetal bone growth. In addition, this type of drug has teratogenic effects in animal experiments, so pregnant women should not use this product. This product can be secreted from breast milk, and the concentration in breast milk is high. It has the potential to cause serious adverse reactions to infants. Lactating women should suspend breastfeeding when using it. Precautions for the elderly: Elderly patients are often accompanied by renal impairment. The use of this product is prone to hepatotoxicity. Therefore, when elderly patients use this product, the dosage should be adjusted according to the degree of renal impairment.

1. When used together with antacids such as sodium bicarbonate, the absorption of this product may be reduced and its activity may be reduced due to the increase in the pH value in the stomach. Therefore, antacids should not be taken within 1 to 3 hours after taking this product. 2. Drugs containing metal ions such as calcium, magnesium, and iron may form insoluble complexes with this product, reducing the absorption of this product. 3. When used together with the general anesthetic methoxyflurane, its nephrotoxicity may be enhanced. 4. When used together with strong diuretics such as furosemide and other drugs, renal damage may be aggravated. 5. When used together with other hepatotoxic drugs (such as anti-tumor chemotherapy drugs), liver damage may be aggravated. 6. The lipid-lowering drugs cholestyramine or colestipol may affect the absorption of this product and must be taken several hours apart. 7. This product may reduce the effectiveness of contraceptives and increase the possibility of extramenstrual bleeding. 8. This product can inhibit the activity of plasma prothrombin, so

Keep in a light-proof and airtight container.

100s

24 months