Diprophylline Tablets
Function and Efficacy
This product has a slightly weaker antiasthmatic effect than theophylline, and its cardiac stimulant effect is only 1/20 to 1/10 of that of aminophylline. It has less effect on the heart and nervous system, and is especially suitable for asthma patients with tachycardia. This product has a direct relaxant effect on respiratory smooth muscle, and its mechanism of action is the same as that of theophylline. In the past, it was believed that it was caused by inhibiting phosphodiesterase, thereby increasing the intracellular cAMP content. In recent years, experiments have shown that the bronchodilator effect of theophylline is partly due to the release of endogenous adrenaline and noradrenaline. In addition, theophylline is a purine receptor blocker that can counteract the contractile effect of adenine and other substances on the respiratory tract. Theophylline can enhance the contractility of the diaphragm, especially when the diaphragm contraction is weak, so it helps to improve respiratory function.
Ingredients
The main ingredients of this product and its chemical name are: The main ingredient of this product is dihydroxypropylphylline, and its chemical name is 1,3-dimethyl-7-(2,3-dihydroxypropyl)-3,7-dihydro-1H-purine-2,6-dione. Its molecular formula is C10H14N4O4, and its molecular weight is 254.25.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| DiprophyllineIngredients |
Its antiasthmatic effect is slightly weaker than that of theophylline, and its cardiac stimulant effect is only 1/20 to 1/10 of that of aminophylline. It has less impact on the heart and nervous system, and is especially suitable for asthma patients with tachycardia. It has a direct relaxant effect on respiratory smooth muscle, and its mechanism of action is the same as that of theophylline, which is partly due to the release of endogenous adrenaline and noradrenaline. In addition, it can enhance the contractility of the diaphragm and help improve respiratory function. More |
479-18-5 | 11 |
Appearance
This product is white tablets.
Indication
It is suitable for relieving wheezing symptoms in bronchial asthma, asthmatic bronchitis, obstructive pulmonary emphysema, etc. It is also used for asthma caused by cardiogenic pulmonary edema. It is especially suitable for asthma cases that cannot tolerate theophylline.
Usage and Dosage
Oral administration. The usual dosage for adults is 0.1-0.2g at a time, 3 times a day; the maximum dosage is 0.5g at a time.
Adverse Reactions
Similar to theophylline, excessive doses may cause nausea, vomiting, irritability, insomnia, tachycardia, arrhythmia, and even fever, dehydration, convulsions, and even respiratory and cardiac arrest.
Precautions
It is contraindicated for patients who are allergic to this product, those with active peptic ulcers and uncontrolled convulsive diseases.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
1. When used in combination with lithium salts, it can increase the renal excretion of lithium and affect the effect of lithium salts. 2. When used in combination with caffeine or other xanthine drugs, it can increase their effects and toxicity.
Storage
Sealed, store in a dry place.
Packaging Specification
0.2g
Validity Period
24 months
Manufacturer
Shanxi Taiyuan Pharmaceutical Co., Ltd.
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Founded in:
2004-01-15 -
Address:
No. 22, Huagong Road, Jinyuan District, Taiyuan City, Shanxi Province -
Tax NO.:
91140100757271910U -
Registered Funds:
215 million yuan -
Website:
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Email: