Mosapride Citrate Tablets

This product is a selective 5-hydroxytryptamine 4 (5-HT4) receptor agonist. It promotes the release of acetylcholine by stimulating the 5-HT4 receptors of the gastrointestinal cholinergic interneurons and the myenteric plexus, thereby enhancing gastrointestinal motility and improving the gastrointestinal symptoms of patients with functional dyspepsia without affecting the secretion of gastric acid. This product has no affinity with dopamine D2, 5-HT1, and 5-HT2 receptors on the brain synaptic membrane, so there are no extrapyramidal side effects caused by the blockade of these receptors. In the toxicology test, the LD50 of oral administration of mosapride to mice was 2004 mg/kg, and the LD50 of intraperitoneal injection was 587.77 mg/kg.

The main ingredient of this product is mosapride citrate.

This product is a white film-coated tablet, which appears off-white after removing the film coating.

This product is a gastrointestinal prokinetic agent, mainly used for functional dyspepsia accompanied by gastrointestinal symptoms such as heartburn, belching, nausea, vomiting, early satiety, upper abdominal distension, etc.; it can also be used for gastroesophageal reflux disease, diabetic gastroparesis and gastric dysfunction in patients with partial gastrectomy.

Oral administration, 1 tablet at a time, three times a day, before meals.

The main symptoms are diarrhea, abdominal pain, dry mouth, rash, fatigue, dizziness, etc. Occasionally, eosinophilia, elevated triglycerides, aspartate aminotransferase (GOT), alanine aminotransferase (GPT), alkaline phosphatase (AKP), and γ-glutamyl transpeptidase (GGT) are seen.

It is contraindicated for those who are allergic to this product.

Precautions for children: This experiment has not been conducted and there are no reliable references. Precautions for pregnancy and lactation: Because its safety has not been determined, this product should be avoided. Precautions for the elderly: Elderly people should be carefully observed when taking the medicine, and if side effects are found, appropriate treatment should be taken immediately, such as reducing the dosage.

The effect of this product may be weakened when used in combination with anticholinergic drugs (such as atropine sulfate, butylscopolamine bromide, etc.).

Keep tightly closed in a cool and dry place.

5mg

36 months

Chengdu Kanghong Pharmaceutical Group Co., Ltd.

• Founded in:

  1996-10-03

• Address:

  No. 108, Shuxi Road, Jinniu District, Chengdu, Sichuan

• Tax NO.:

  91510100633116839D

• Registered Funds:

  919.463954 million yuan

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