Atenolol Tablets
Function and Efficacy
It is a selective β1-adrenergic receptor blocker with no membrane stabilizing effect and endogenous sympathomimetic activity. However, it does not inhibit the bronchodilator effect of isoproterenol. Its mechanism of lowering blood pressure and reducing myocardial oxygen consumption is the same as that of propranolol. Large-scale clinical trials have confirmed that atenolol can reduce the mortality rate of acute myocardial infarction within 0 to 7 days. The therapeutic dose has no significant inhibition on myocardial contractility.
Ingredients
The main chemical component is Atenolol. The chemical name is 4-[3-[(1-methylethyl)amino-2-hydroxy]propoxy]phenylacetamide
Appearance
This product is a white tablet or sugar-coated tablet, which appears white after removing the sugar coating.
Indication
It is used to treat hypertension, angina pectoris, myocardial infarction, and can also be used for arrhythmia, hyperthyroidism, and pheochromocytoma.
Usage and Dosage
Oral. The usual dosage for adults is 6.25-12.5 mg (1/4-1/2 tablet) each time, twice a day, and then increase or decrease to 50-200 mg (2-8 tablets) as needed and tolerated. See the instructions for details.
Adverse Reactions
In patients with myocardial infarction, the most common adverse reactions are hypotension and bradycardia; other reactions may include dizziness, cold limbs, fatigue, weakness, gastrointestinal discomfort, depression, hair loss, thrombocytopenia, psoriasis-like skin reactions, psoriasis exacerbation, rash and dry eyes, etc. Rarely, it may cause heart block in sensitive patients.
Precautions
1. II-III degree heart block. 2. Cardiogenic shock. 3. Sick sinus syndrome and severe sinus bradycardia.
Special Population Medication
Precautions for children: Children should start with a small dose of 0.25~0.5mg/kg, twice a day. Pay attention to monitoring heart rate and blood pressure. Precautions for pregnancy and lactation: This product can pass the placental barrier and appear in the umbilical cord blood. There is a lack of research on the use of this drug in the first 3 months, and the possibility of fetal damage cannot be ruled out. Long-term use of this drug by pregnant women is related to intrauterine growth retardation of the fetus. This drug has a significant aggregation effect in breast milk, and lactating women should be cautious when taking it. Precautions for the elderly: The required dose can be reduced, especially for patients with renal decline.
Drug Interactions
When used in combination with other antihypertensive drugs and diuretics, their antihypertensive effect can be enhanced. Be especially cautious when using Class I antiarrhythmic drugs, verapamil, and anesthetics. β-blockers can aggravate the rebound of hypertension caused by discontinuation of clonidine. If the two drugs are used in combination, this drug should be discontinued a few days before discontinuation of clonidine. If this drug is used to replace clonidine, the course of β-blocker treatment should be started a few days after stopping taking clonidine.
Storage
Keep sealed.
Packaging Specification
50mg
Validity Period
24 months
Manufacturer
EMeiShan Tonghui Pharmaceutical Co., Ltd.
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Founded in:
2002-03-29 -
Address:
Tonghui Road, Processing, Warehousing and Logistics Park, Emeishan City -
Tax NO.:
91511181621167487U -
Registered Funds:
54.138461 yuan -
Website:
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Email: