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Levofloxacin Hydrochloride Tablets

Function and Efficacy

This product is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA gyrase (bacterial topoisomerase II) and hinder bacterial DNA replication. This product has the characteristics of a broad antibacterial spectrum and strong antibacterial effect. It has strong antibacterial activity against most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, and Gram-negative bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, and Neisseria gonorrhoeae. It also has good antibacterial effects on some methicillin-sensitive Staphylococci, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococci, and Legionella, Mycoplasma, and Chlamydia, but has poor effects on anaerobic bacteria and enterococci.

Ingredients

The main ingredient of this product is levofloxacin hydrochloride

Name Description Content CAS NO. Manufacturer
Levofloxacin hydrochlorideIngredients

This product is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA gyrase (bacterial topoisomerase II) and hinder bacterial DNA replication. It has the characteristics of a broad antibacterial spectrum and strong antibacterial effect. It has good antibacterial effects on most Enterobacteriaceae, some methicillin-sensitive Staphylococci, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococcus and other Gram-positive bacteria, Legionella, Mycoplasma, Chlamydia, but has poor effects on anaerobic bacteria and enterococci.

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177325-13-2 18

Appearance

This product is a film-coated tablet, which appears off-white or light yellow after removing the film.

Indication

This product is suitable for the following mild and moderate infections caused by sensitive bacteria: respiratory system infections: acute bronchitis, acute exacerbation of chronic bronchitis, diffuse bronchiolitis, bronchiectasis and infection, pneumonia, tonsillitis (peritonsillar abscess); urinary system infections: pyelonephritis, complicated urinary tract infection, etc.; reproductive system infections: prostatitis, acute epididymitis, intrauterine infection, adnexitis, pelvic inflammatory disease (metronidazole can be used in combination when anaerobic infection is suspected); skin and soft tissue infections: infectious impetigo, cellulitis, lymphangiitis (nodal inflammation), subcutaneous abscess, perianal abscess, etc.; intestinal infections: bacillary dysentery, infectious enteritis, salmonella enteritis, typhoid and paratyphoid, etc.; other infections: trauma, burns and postoperative wound infection, abdominal infection (use metronidazole in combination when necessary), mastitis, cholecystitis, cholangitis, bone and joint infection and ENT infection, etc.

Usage and Dosage

Adults take 200mg to 300mg (2 to 3 tablets) per day, divided into 2 to 3 times, 1 tablet each time. For patients with more serious conditions, the maximum daily dose can be increased to 600mg (6 tablets), divided into 3 times. In addition, the dose can be increased or decreased appropriately according to the type of infection and symptoms.

Adverse Reactions

During medication, symptoms such as nausea, vomiting, abdominal discomfort, diarrhea, loss of appetite, abdominal pain, abdominal distension, insomnia, dizziness, headache and other neurological symptoms, as well as rash, itching and other symptoms may occur. Transient liver function abnormalities may also occur, such as increased serum transaminase and increased serum total bilirubin. The incidence of the above adverse reactions is between 0.1% and 5%. Occasionally, blood urea nitrogen rises, fatigue, fever, palpitations, abnormal taste, etc., which are generally tolerated and disappear quickly after the end of the treatment.

Precautions

It is contraindicated for patients who are allergic to quinolones, pregnant or lactating women, and patients under 18 years of age.

Special Population Medication

Precautions for children: Precautions for children during pregnancy and lactation: Precautions for pregnant and lactating women Precautions for the elderly: Elderly patients should use with caution. Generally, 100 mg is used once, twice a day, and the interval between medications should be noted.

Drug Interactions

Not yet clear

Storage

Keep away from light and store in sealed container.

Packaging Specification

0.1g (based on C18H20FN3O4)

Validity Period

24 months

Manufacturer

Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical General

  • Founded in:

    1973-07-01
  • Address:

    No. 88, Yunxiang Road, Tonghe Street, Baiyun District, Guangzhou
  • Tax NO.:

    91440101714253245D
  • Registered Funds:

    -
  • Website:

  • Email:

Other Drugs of Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical General

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