Bifendate Tablets

This product is an intermediate in the synthesis of Schisandra chinensis C. Oral administration of 150-200 mg/kg of this product to mice can reduce liver damage and elevated alanine aminotransferase (ALT) caused by carbon tetrachloride. It has an inhibitory effect on liver microsomal lipid peroxidation caused by carbon tetrachloride and the metabolic conversion of carbon tetrachloride into carbon monoxide, and reduces the consumption of reduced coenzyme II and oxygen in the metabolic process of carbon tetrachloride, thereby protecting the structure and function of the hepatocyte biomembrane. This product can also reduce the elevation of liver ALT induced by prednisone and promote liver regeneration in mice with partial hepatectomy. The enzyme-lowering effect of this product does not directly inhibit the activity of serum and liver ALT, nor does it accelerate the inactivation of ALT in the blood, which may be a reflection of the reduction of liver tissue damage. This product has a significant induction effect on the activity of cytochrome P450 enzymes, thereby enhancing the detoxification ability of carbon tetrachloride and certain carcinogens. It has an effect on improving protein metabolism in some hepatitis patients, increasing albumin and reducing globulin. It has no negative conversion effect on HbsAg and HbeAg, and cannot shrink the enlarged liver and spleen.

Biphenyl diester. Chemical name: 4,4-dimethoxy-5,6,5,6-bis(methylenedioxy)biphenyl-2,2-dicarboxylic acid dimethyl ester. Molecular weight: 418.36 Molecular formula: C20H18O10

This product is white tablets.

This product has a certain effect on the improvement of the main symptoms of hepatitis such as liver pain, fatigue, abdominal distension, etc., but it is ineffective for changes in hepatosplenomegaly. It is suitable for patients with persistent hepatitis and long-term single alanine aminotransferase abnormalities.

Oral administration: 25 mg each time, 75 to 150 mg per day, usually 3 times a day.

In some cases, mild nausea and occasional rash may occur after taking the drug.

1. It is contraindicated for those who are allergic to this product; 2. It is contraindicated for those with cirrhosis; 3. It is contraindicated for pregnant and lactating women.

Precautions for children: Reduce the dosage for children. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: Elderly patients should use this product with caution.

Not yet clear.

Keep away from light and store in airtight container.

25mg

Tentative 24 months

Dandong Yichuang Pharmaceutical Co., Ltd.

• Founded in:

  2003-12-30

• Address:

  No. 6, Yongxiang Street, Donggang City, Dandong City, Liaoning Province

• Tax NO.:

  9121060075578371X5

• Registered Funds:

  7.142857 million yuan

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