Naftopidil Tablets

Naftopidil is a selective α1 receptor antagonist that can inhibit the increase in blood pressure caused by α1 receptors. Pharmacodynamic tests have shown that this product has a hypotensive effect on a variety of hypertensive animal models, with a long duration of hypotension, and does not cause reflex tachycardia during hypotension. No obvious first-dose effect or drug resistance was observed after multiple oral administrations. The results of cardiac hemodynamic tests showed that this product can reduce the total peripheral resistance of anesthetized open-chest dogs, dilate peripheral blood vessels, and have no significant effect on cardiac output. This product can also relieve the sympathetic tension of the prostate and urethra caused by the excitement of the receptor through the α1 receptor blocking effect, reduce the intraurethral pressure, and improve symptoms such as urination disorders caused by benign prostatic hyperplasia.

(±)-1-[4-(2-methoxyphenyl)piperazinyl]-3-(1-naphthyloxy)-2-propanol

This product is white tablets

Used to relieve urinary tract obstruction symptoms caused by benign prostatic hyperplasia (BPH).

Oral. Usually the initial dosage for adults is 25 mg (1 tablet) once a day, taken before bedtime. The dosage can be adjusted appropriately according to the clinical efficacy. The maximum daily dosage should not exceed 75 mg (3 tablets). Elderly patients should start with a low dose (12.5 mg/day) and pay attention to monitoring.

The main symptoms include dizziness, vertigo on standing, heavy head, headache, tinnitus, constipation, stomach discomfort, edema, chills, increased AST and increased ALT.

This product is contraindicated for patients who are allergic to any ingredient or have low blood pressure.

Precautions for children: The efficacy and safety of the drug for children have not been established, and it is not recommended for children. Precautions for pregnancy and lactation: The efficacy and safety of the drug for pregnant and lactating women have not been established. Precautions for the elderly: Elderly patients generally have reduced liver function, and this product is mainly metabolized in the liver. Therefore, elderly patients should use it with caution according to the situation, and the dosage should be reduced when starting the medication (for example, taking 12.5 mg, etc.).

This product has a synergistic antihypertensive effect when used in combination with diuretics and antihypertensive drugs. The dosage should be reduced when they must be used together.

Store in a sealed container at room temperature. The shelf life is tentatively 18 months.

25mg

18 months

Hubei Qianjiang Pharmaceutical Co., Ltd.

• Founded in:

  2009-09-18

• Address:

  No. 1, Zhanghua South Road, Qianjiang City

• Tax NO.:

  91429005695102248D

• Registered Funds:

  300 million yuan

• Website:

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