Potassium chloride tablets
Function and Efficacy
Potassium chloride is an electrolyte supplement. Potassium is the main cation in cells and an important component for maintaining intracellular osmotic pressure. The concentration in cells is about 150-160 mmol/L, and the concentration in extracellular fluid is lower, only 3.5-5.0 mmol/L. The body mainly relies on Na, K, and ATP enzymes on the cell membrane to maintain the difference in K and Na+ concentrations inside and outside the cells. The acid-base balance in the body affects potassium metabolism. For example, when acidosis occurs, H+ enters the cell. In order to maintain the potential difference inside and outside the cell, K+ is released to the outside of the cell, causing or aggravating hyperkalemia. The normal intracellular potassium ion concentration and concentration difference are closely related to certain functions of the cell. Potassium is involved in the regulation of acid-base balance, the synthesis of sugars and proteins, and the conversion of adenosine diphosphate into triphosphate.
Ingredients
The main ingredient of this product and its chemical name: potassium chloride.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Potassium chlorideIngredients |
Potassium chloride is an electrolyte supplement. Potassium is the main cation in cells and an important component for maintaining intracellular osmotic pressure. The concentration in cells is about 150-160mmol/L, and the concentration in extracellular fluid is lower, only 3.5-5.0mmol/L. The body mainly relies on Na, K, and ATPase on the cell membrane to maintain the concentration difference between K and Na+ inside and outside the cell. The acid-base balance in the body affects potassium metabolism. For example, when acidosis occurs, H+ enters the cell. In order to maintain the potential difference between the inside and outside of the cell, K+ is released to the outside of the cell, causing or aggravating hyperkalemia. The normal intracellular potassium ion concentration and concentration difference are closely related to certain functions of the cell. Potassium is involved in the regulation of acid-base balance, the synthesis of sugar and protein, and the conversion of adenosine diphosphate to adenosine triphosphate. More |
7447-40-7 | 39 |
Appearance
This product is white tablet or sugar-coated tablet.
Indication
1 Treatment of hypokalemia Hypokalemia caused by various reasons, such as insufficient food intake, vomiting, severe diarrhea, use of potassium-excreting diuretics, hypokalemic familial periodic paralysis, long-term use of glucocorticoids and supplementation of hypertonic glucose, etc. 2 Prevention of hypokalemia When patients have potassium loss, especially if hypokalemia is harmful to patients (such as patients using digitalis drugs), preventive potassium salt supplementation is required, such as eating very little, severe or chronic diarrhea, long-term use of adrenocortical hormones, potassium-losing nephropathy, Bartter syndrome, etc. 3 Digitalis poisoning causes frequent, multi-source premature beats or rapid arrhythmias.
Usage and Dosage
Oral potassium salts are used to treat mild hypokalemia or as preventive medication. The usual dose for adults is 0.5-1g (6.7-13.4mmol) each time, 2-4 times a day, after meals, and the dose is adjusted according to the condition. The maximum daily dose for adults is 6g (80mmol).
Adverse Reactions
1 Oral administration may cause gastrointestinal irritation symptoms, such as nausea, vomiting, throat discomfort, chest pain (esophageal irritation), abdominal pain, diarrhea, and even peptic ulcer and bleeding. It is more likely to occur on an empty stomach, in large doses, or in patients with existing gastrointestinal diseases. 2 Hyperkalemia should be noted in patients with existing renal impairment.
Precautions
1. Patients with hyperkalemia. 2. Patients with acute renal insufficiency or chronic renal insufficiency.
Drug Interactions
1. Adrenal glucocorticoids, especially those with more obvious mineralocorticoid effects, adrenal mineralocorticoids and adrenocorticotropic hormone (ACTH), can promote urinary potassium excretion, and reduce the efficacy of potassium salts when used together. 2. Anticholinergic drugs can aggravate the gastrointestinal irritation of oral potassium salts, especially potassium chloride. 3. Non-steroidal anti-inflammatory analgesics aggravate the gastrointestinal reactions of oral potassium salts. 4. When using stored blood (30mmol/L of potassium for less than 10 days of storage, 65mmol/L of potassium for more than 10 days of storage), potassium-containing drugs and potassium-sparing diuretics together, the chance of hyperkalemia increases, especially in patients with renal damage. 5. Angiotensin converting hormone
Storage
Keep tightly closed.
Packaging Specification
0.25g