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Milk Thistle Extract

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

22888-70-6

Grade:

Food Grade

Content:

80%

Port:

SHANGHAI

Brand:

Benepure

Packaging:

25kg/Cardboard Drum

Price valid (until):

2022-08-12

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Neohesperidin Dihydrochalcone,Baicalin,Cephalotaxine,Diosmin,Naringin,Cranberry Extract

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Product Name: Milk Thistle Extract
    Specification: 80.0% Silymarin Test by UV
    Efficacy: Liver protection

    Sources and Habitat
    Silybum marianum (L.) Gaertn belongs to the Asteraceae family (Compositae). It is native to southern Europe, southern Russia, Asia Minor and North Africa. It has been naturalized to North and South America.

    Descriptions and Specifications of Product
    Content Specifications: 80% Silymarin Test by UV
    30% Silybin (Silibinin) Test by HPLC
    For this product, EDMF is available
    Silibinin
    Molecular Formula: C25H22O10
    Molecular Mass: 482.43
    CAS No.: 22888-70-6
    Constititional Formula:
    Milk Thistle Extract
    Isosilybin
    Molecular Formula: C25H22O10
    Molecular Mass: 482.43
    CAS No.: 22888-70-6
    Constititional Formula:
    Milk Thistle Extract
    Silychristin
    Molecular Formula: C25H22O10
    Molecular Mass: 482.43
    CAS No.: 72581-71-6
    Constititional Formula:
    Milk Thistle Extract
    Silydianin
    Molecular Formula: C25H22O10
    Molecular Mass: 482.43
    CAS No.: 22888-70-6
    Constititional Formula:
    Milk Thistle Extract
    Indications and Uses
    It has the functions of protecting liver cell membrane and improving the liver function. Meanwhile, it has the function of detoxification, reducing the blood fat, benefiting the gallbladder, protecting the brain and removing the free radical of body and active constituent.

    Safety Concerns
    The Agency for Healthcare Research and Quality reviewed the effects of milk thistle on liver disease and cirrhosis, noting that serious adverse reactions are virtually unheard of. The most common reported complaints were gastrointestinal disturbances, but the overall incidence was no different from placebo. Allergic reactions, ranging from pruritus and rash to eczema and anaphylaxis, are rare.

    Dosage Information
    Most clinical trials have used daily dosages of 420 to 480 mg silymarin, divided into two or three doses daily. Until the specific effects of each of the flavonolignans is known and products are available that contain standardized ratios of these components, the optimal dosage will remain unknown.

    Basic Info
    Product Name:

    Silybin

    Other Name:

    4H-1-Benzopyran-4-one,2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)-;4-Chromanone,3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl]-;Silybin;4H-1-Benzopyran-4-one,2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-,[2R-[2α,3β,6(2R*,3R*)]]-;1,4-Benzodioxin,4H-1-benzopyran-4-one deriv.;(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Silybine;Silymarin I;7C3MT;Silliver;Silymarine I;Silibinin;Silymarin MZ 80;Silybum substance E6;Silybin A;Silybin b1;Silibinin A;Mepasil;Realsil;142796-20-1;11054-49-2;11076-05-4;11076-06-5;22888-69-3;27359-03-1;28577-40-4;29832-10-8;37574-50-8;50976-99-3;87725-90-4

    CAS No.:

    22888-70-6

    Molecular Formula:

    C25H22O10

    InChIKeys:

    InChIKey=SEBFKMXJBCUCAI-HKTJVKLFSA-N

    Molecular Weight:

    482.44

    Exact Mass:

    482.44

    EC Number:

    245-302-5

    UNII:

    33X338MNE4

    NSC Number:

    651520

    DSSTox ID:

    DTXSID5023580|DTXSID8026018

    ATC Code:

    A - Alimentary tract and metabolism

    HScode:

    2932999099

    Characteristics
    PSA:

    155

    XLogP3:

    2.4

    Appearance:

    solid

    Density:

    1.5±0.1 g/cm3

    Melting Point:

    158 °C

    Boiling Point:

    793°C at 760 mmHg

    Flash Point:

    274.5±26.4 °C

    Refractive Index:

    1.684

    Water Solubility:

    54mg/L(24.99 ºC)

    Storage Conditions:

    −20°C

    Vapor Pressure:

    1.63E-26mmHg at 25°C

    Toxicity:

    LD50 intravenous in mouse: 1056mg/kg

    Specific rotation:

    D20 +11° (c = 0.25 in acetone + alcohol)

    Collision Cross Section:

    213.6 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Neohesperidin Dihydrochalcone,Baicalin,Cephalotaxine,Diosmin,Naringin,Cranberry Extract

    Location:

    99# Jirui 3rd Road, High-tech District,Chengdu, Sichuan Prov., China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A

    Average lead Time:

    7

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    101-200

    Year of Establishment:

    2004

    Certifications:

    The registered trademark of company,The registered trademark of product

    Sichuan Benepure Pharmaceutical Co.,Ltd. is a professional manufacturer and research institution, serving the pharmaceutical, veterinary, cosmetics, natural foods and animal nutrition industries by providing a diverse range of over 300 unique beneficial ingredients, headquartered in China(Sichuan) Free Trade Area. 


    Benepure prides itself on manufacturing system standard above the GMP certification of many countries, meeting exact demands of various international regulations. Benepure is now manufacturing and supplying over 300 products of unsurpassed quality and maintaining two plants in China.


    Benepure is dedicated to the reduction of emission pollution and environmental protection during the manufacturing process for long-term sustainability of social and economic development. 

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    ISO Certified Reference Material Natural Extract Silibinin Powder CAS 22888-70-6 with 99% Purity

    100 G Oct 11, 2023
    India

    Milk Thistle Extract 80% UV

    1.00 MT Jun 29, 2026
    Post an enquiry for this product
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