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Ursodeoxycholic acid 128-13-2

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CAS No.:

128-13-2

Packaging:

25kg/drum

Price valid (until):

2022-10-24

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SHANDONG LOOK CHEMICAL CO.,LTD

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Choleretic drugs

Choleretic drugs are generally divided into two major categories: Choleretic agents and liquid-increase Choleretic agent. The former refers to the drug can promote the secretion of bile. The latter one refers only to those drugs which can increase capacity without increasing bile. The most commonly used Choleretic drugs is mainly cholic acid class-based such as sodium dehydroepiandrosterone acid, chenodeoxycholic acid and ursodeoxycholic acid and so on.
Ursodeoxycholic acid is a chemical agent of natural bile acid which is isolated from the bile of bear. It is the stereo-isomer of chenodeoxycholic acid. It has a similar litholysis effect, efficacy as chenodeoxycholic acid. However, it has a short course of treatment and a small dose. It is bound with taurine in the bile in vivo, and is a hydrophilic bile acids as well as a dissolving agent of cholesterol. It can reduce the secretion of cholesterol in the liver, lower the saturation content of cholesterol in bile, promote the secretion of bile acids, and increase the solubility of cholesterol in the bile so that cholesterol gallstones can be dissolved or prevented. Moreover, it can increase the secretion amount of bile, and have a choleretic effect by relaxing the bile duct mouth sphincter which smoothen the discharge of calculus. This product, however, cannot dissolve other types of gallstones. Ursodeoxycholic acid is useful in the treatment of cholesterol stones, hyperlipidemia, bile secretion disorders, primary biliary cirrhosis, chronic hepatitis, bile reflux gastritis and prevention of liver allograft rejection and reaction. The calculus-dissolving effect of this product is slightly weaker than the CDCA.

Basic Info

Product Name:

Ursodeoxycholic acid

Other Name:

Cholan-24-oic acid,3,7-dihydroxy-,(3α,5β,7β)-;5β-Cholan-24-oic acid,3α,7β-dihydroxy-;5β-Cholanic acid,3α,7β-dihydroxy-;(3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid;17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7β-diol;Ursocholic acid,deoxy-;Ursodeoxycholic acid;Ursodesoxycholic acid;3α,7β-Dihydroxy-5β-cholan-24-oate;3α,7β-Dihydroxycholanic acid;3α,7β-Dihydroxy-5β-cholanic acid;3α,7β-Dihydroxy-5β-cholanoic acid;7β-Hydroxylithocholic acid;3α,7β-Dihydroxy-5β-cholan-24-oic acid;Urso;Actigall;Ursodiol;Deursil;Desocol;Ursofalk;Ursochol;Cholit-Ursan;Ursacol;Destolit;Paptarom;Arsacol;Urdes;Solutrat;Lyeton;Ursobilin;Ursolvan;Ursodamor;Delursan;Desol;Litursol;NSC 683769;Adursal;UDCA;Ursic acid;Ursosan;Ursocol;Ursogall;Urosiol;50809-41-1;80225-86-1;2599839-20-8

CAS No.:

128-13-2

Molecular Formula:

C24H40O4

InChIKeys:

InChIKey=RUDATBOHQWOJDD-UZVSRGJWSA-N

Molecular Weight:

392.57200

Exact Mass:

392.57

EC Number:

204-879-3

UNII:

724L30Y2QR

DSSTox ID:

DTXSID6023731

NCI Thesaurus Code:

C1818

ATC Code:

A05AA02|A - Alimentary tract and metabolism

HScode:

2918199090

Categories:

Digestive System Drugs

Characteristics

PSA:

77.76000

XLogP3:

4.47790

Appearance:

Solid

Density:

1.128 g/cm3

Melting Point:

203 °C

Boiling Point:

547.1ºC at 760mmHg

Flash Point:

298.8ºC

Refractive Index:

1.543

Water Solubility:

ethanol: 50 mg/mL, clear

Storage Conditions:

Store in a tightly closed container. Store in a cool, dry area away from incompatible substances.

Vapor Pressure:

0mmHg at 25°C

Collision Cross Section:

208.98 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|198.7 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|200.9 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|198.3 Å² [M-H]- [CCS Type: DT, Method: single field calibrated]|186.8 Å² [M+H-2H2O]+ [CCS Type: DT, Method: single field calibrated]|200.2 Å² [M+HCOO]- [CCS Type: DT, Method: single field calibrated]|205.7 Å² [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|199.4 Å² [M+Na-H+Cl]- [CCS Type: DT, Method: single field calibrated]|203.2 Å² [M+Na-H+HCOO]- [CCS Type: DT, Method: single field calibrated]

See More Ursodeoxycholic acid Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ursodeoxycholic acid Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

Location:
hisense intelligence valley,no 2116,of phoenix road

Payment Terms:
TT against copy of documents,D/P,L/C

Average lead Time:
7

Total Annual Revenue:
Less than $1 million

Total Employees:
11-50

Year of Establishment:
2017

SHANDONG LOOK CHEMICAL CO.LTD, a new chemical enterprise in researching, manufacturing and supplying of chemicals located in beautiful “Spring City”-Jinan.Our company mainly working on the researching new-born APIs, intermediate ( especially Carbohydrate derivatives series). Meanwhile, we made huge breakthrough in industries of food, feed additives, cosmetics ,dye and industrial chemicals. Our company enjoyed great reputation both domestic and abroad under the belief of “Integrity management,Quality controlling and Customer orientation”. Web : www.chinalookchemical.com

We had been cooperated with NingXia University and Shandong University on more than ten projects for years and which had been in mass production on the market. We now have more than 80 people in our team and built research center in Jinan and Ningxia. Our manufacturing site allocated in chemical industry parks of Zhangqiu, Heze, Dezhou and Ningxia Fine Chemical Park. We strictly complying with ISO9001 and ISO 2000 standard in manufacturing process, our lab and workshop tightly in accordance with GMP standard.Our products best selling in Europe, South and North America,Asia pacific area and Africa. We sincerely welcome new and regular customers around the world visit us for business negotiation.

Inquiry History

12 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	URSODEOXYCHOLIC ACID	10.00 KG	Mar 6, 2024
Canada	URSODEOXYCHOLIC AC	1.5 MT	Apr 25, 2026
United States	Ursodeoxycholic acid	500 G	Sep 16, 2025
Lesotho	Ursodeoxycholic Acid	1 TON	May 21, 2025
Finland	Ursodeoxycholic acid	100 G	Mar 21, 2025
India	URSODEOXYCHOLIC ACID	300.00 KG	Sep 10, 2024
India	udca	25 KG	Sep 11, 2023
India	URSODEOXYCHOLIC ACID	500.00 KG	Jul 26, 2024
India	Ursodeoxycholic Acid	1500 KG	May 17, 2024
India	Acarbose	10.00 KG	Mar 6, 2024
India	Upadacitinib	10.00 KG	Mar 6, 2024
India	Ripretinib	10.00 KG	Mar 6, 2024

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Ursodeoxycholic acid 128-13-2

Product Description

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