Manumycin A
52665-74-4
90%
2026-07-11
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Manumycin A Cat No CEI-0480 Description An antibiotic Isolated from Streptomyces parvulus. A Potent, selective and competitive cell permeable rasfarnesyltransferase (FTase) inhibitor (IC50 = 30 nM). Does not affect geranylgeranyltransferase (GGTase) (IC50 = 180 µM). Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19 µM).µM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. Alias NSC-622141; UFC 1C Appearance Off-white solid Product Overview A potent ras farnesyltransferase (FTase) inhibitor CAS No 52665-74-4 Molecular Weight 302.78 Purity >90% by NMR Storage -20 centigrade Synonyms NSC-622141; UFC 1C Targets FNTB Molecular Formula C 31 H 38 N 2 O Solubility DMSO (100 mM) Shipping Conditions Gel pack category Specialty Chemicals(c26) cas_num 52665-74-4 Basic Info-
Product Name:
Manumycin
Other Name:2,4-Decadienamide,N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-,(2E,4E,6R)-;Manumycin;2,4-Decadienamide,N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-,(2E,4E,6R)-;7-Oxabicyclo[4.1.0]heptane,2,4-decadienamide deriv.;(2E,4E,6R)-N-[(1S,5S,6R)-5-Hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-2,4-decadienamide;UCF 1C;Manumycin A;(-)-Manumycin A;NSC 622141
CAS No.:52665-74-4
Molecular Formula:C31H38N2O7
InChIKeys:InChIKey=TWWQHCKLTXDWBD-MVTGTTCWSA-N
Molecular Weight:550.6 g/mol
Exact Mass:550.64
Categories:
Characteristics-
PSA:
145 Ų
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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