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API 99% Oseltamivir CAS 196618-13-0 for Anti-Influenza

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CAS No.:

196618-13-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Xi'an

Brand:

TGY

Packaging:

1kg/foil bag, 25kg/drum

Price valid (until):

2024-04-07

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Xi'an Tian Guangyuan Biotech Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Minoxidil,Paracetamol,Diclofenac sodium,fenbendazole,Ivermectin

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Product Description
Seller Information

Description

Product Detail

What is Oseltamivir ?

Product name:Oseltamivir
MF:   C16H28N2O4
MW:   312.4
CAS:   196618-13-0

oseltamivir phosphate (oseltamivirphosphate) is a neuraminidase inhibitor anti-influenza drug marketed in 1999 under the trade name Tamiflu(Tamiflu). It was first discovered by GileadSciences, then developed in partnership with Roche and approved for sale in the United States. Oseltamivir phosphate is the first orally effective neuraminidase inhibitor that is effective against both influenza A and B viruses. Oral oseltamivir is rapidly catalyzed by liver and intestinal esterase to its active metabolite, olchemicalbook seltamivir carboxylate. Oseltamivir carboxylate has a configuration similar to the transition state of neuraminic acid and binds competitively to the active site of influenza virus neuraminidase (NA). It is therefore a potent and highly selective influenza virus NA inhibitor (NAIs), which reduces the transmission of influenza A or B viruses mainly by interfering with the release of viruses from infected host cells. Therefore, oseltamivir phosphate is a precursor drug. At present, oseltamivir phosphate (Tamiflu) is still recognized as one of the most effective drugs on the market for the treatment of influenza A (H1N1), which was approved for market in China in July 2004.

Product Application

Oseltamivide is rapidly metabolized to oseltamivir carboxylate by absorption through the gastrointestinal tract and at least 75 % of the oral dose is involved in systemic circulation in the form of oseltamivircarboxylate

The active ingredient Is a potent and unique neuraminidase inhibitor that acts on all aspects of influenza virus infection and prevents the replication of all clinically relevant strains of influenza A or B viruses.

In vitro in very low nanomolarconcentrations that have inhibitory effect. The active metabolite was observed to inhibit the growth of influenza virus in vitro and it was also observed in vivo to inhibit the replication and pathogenicity of influenza virus.

Oseltamivide phosphate reduces the spread of influenza A or B viruses by inhibiting the release of the virus from the infected cells.

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Basic Info

Product Name:

Oseltamivir

Other Name:

1-Cyclohexene-1-carboxylic acid,4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-,ethyl ester,(3R,4R,5S)-;1-Cyclohexene-1-carboxylic acid,4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-,ethyl ester,[3R-(3α,4β,5α)]-;GS 4104;Oseltamivir;Tamvir;Tamiflu-Free;GOP-A-Flu;(-)-Oseltamivir;Enfluvir;Ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate;ZINC 039295508;Ebilfumin

CAS No.:

196618-13-0

Molecular Formula:

C16H28N2O4

InChIKeys:

InChIKey=VSZGPKBBMSAYNT-RRFJBIMHSA-N

Molecular Weight:

312.4

Exact Mass:

312.40

EC Number:

1308068-626-2

UNII:

20O93L6F9H

DSSTox ID:

DTXSID9044291

NCI Thesaurus Code:

C62061

ATC Code:

J05AH02|J - Antiinfectives for systemic use

Categories:

Antivirals

Characteristics

PSA:

90.6

XLogP3:

Appearance:

Solid

Density:

1.08±0.1 g/cm3(Predicted)

Melting Point:

107-108 °C

Boiling Point:

473.3±45.0 °C(Predicted)

Flash Point:

223.2±31.5 °C

Refractive Index:

1.529

Water Solubility:

H2O: soluble

Storage Conditions:

Store the capsules at 25 deg C (77 deg F); excursions permitted to 15 deg to 30 deg C (59 deg to 86 deg F).

Vapor Pressure:

1.3X10-8 mm Hg at 25 deg C (est)

Henrys Law Constant:

Henry's Law constant = 2.9X10-16 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa = 7.7 at 25 °C (primary amine)

Collision Cross Section:

180.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

Mol wt: 410.40. White crystalline solid /Phosphate/|Hydroxyl radical reaction rate constant = 1.3X10-10 cu cm/molecule-sec at 25 °C (est)

See More Oseltamivir Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Oseltamivir Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Minoxidil,Paracetamol,Diclofenac sodium,fenbendazole,Ivermectin

Location:
I-City unit 3, South of Tangyan Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
51-100

Year of Establishment:
2015

Certifications:
HACCP,Halal,GMP,ISO

Company Profile

XI'AN TIANGUANGYUAN BIOTECH CO., LTD. is specialized in researching, producing and selling Herbal Extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and Food Additives etc. Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. It is aiming of benefiting the world with lowest price but best products.We are keeping overcritical on the quality and persisting in the profession all the time. TGY owns two standardized production workshops, advanced multi-function extractors and juice concentrate equipment, covering 12,000㎡ annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service.

So far, we have 10 years experience for export in this field and have good relationship with regular customers from countries and regions in the world. Our company has got independent Import & Export License and has built good relationship with international expresses, as well as some air and sea shipping agents to provide timely and professional service for all clients.

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