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Bexarotene

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

153559-49-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ShangHai

Packaging:

drums

Price valid (until):

2023-11-12

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Di-n-butyl naphthalene-2,6-dicarboxylate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer?s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

    ItemsSpecifications
    Melting point 230-231°C
    Boiling point 489.7±44.0 °C(Predicted)
    density 1.042
    storage temp. -20°C
    solubility Soluble in DMSO and ethanol
    form White powder
    pka4.08±0.10(Predicted)
    color white to beige
    Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.

    Basic Info
    Product Name:

    Bexarotene

    Other Name:

    Benzoic acid,4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-;4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid;LGD 1069;LG 1069;LG 100069;Bexarotene;Targrexin;Targretyn;RO 26-4455;LG 69;Targretin;LG 69 (retinoid);Targret;SR 11247

    CAS No.:

    153559-49-0

    Molecular Formula:

    C24H28O2

    InChIKeys:

    InChIKey=NAVMQTYZDKMPEU-UHFFFAOYSA-N

    Molecular Weight:

    348.48

    Exact Mass:

    348.48

    UNII:

    A61RXM4375

    NSC Number:

    747528

    DSSTox ID:

    DTXSID1040619

    NCI Thesaurus Code:

    C1635

    Color/Form:

    Off-white to white powder

    ATC Code:

    L01XF03|L01XX25|L - Antineoplastic and immunomodulating agents

    HScode:

    29163990

    Characteristics
    PSA:

    37.3

    XLogP3:

    7.6

    Appearance:

    white to beige

    Density:

    1.042

    Melting Point:

    224-226 °C @ Solvent: Ethyl acetate, Hexane

    Boiling Point:

    489.7±44.0 °C(Predicted)

    Flash Point:

    229.5±23.1 °C

    Refractive Index:

    1.556

    Water Solubility:

    Soluble in DMSO and ethanol

    Storage Conditions:

    -20°C Freezer

    Vapor Pressure:

    3.5X10-9 mm Hg at 25 deg C (est)

    Henrys Law Constant:

    Henry's Law constant = 8.1X10-9 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa = 4.2 (carboxylic acid) (est)

    Experimental Properties:

    Also reported as white crystals, mp 234 °C|Hydroxyl radical reaction rate constant = 6.9X10-11 cu cm/molecule-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Di-n-butyl naphthalene-2,6-dicarboxylate

    Location:

    1208# HuaCe Building-B,Wuchanggang Road,XIHU District,Hangzhou City,Zhejiang Province ,China

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    5-10

    Year of Establishment:

    2023

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Bexarotene

    150 G Jun 23, 2025
    Post an enquiry for this product
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