Raw Materials Inosine CAS 58-63-9 99% Powder Evergreen EGC-Inosine Raw Powder

Nucleoside Structure: Inosine is composed of a purine base (hypoxanthine) attached to a ribose sugar molecule through a β-N9-glycosidic bond, forming a nucleoside.

Intermediate in Nucleotide Metabolism: Inosine is an intermediate in the metabolism of purine nucleotides. It can be formed by the deamination of adenosine or the breakdown of adenosine monophosphate (AMP).

Endogenous Signaling Molecule: Inosine serves as an endogenous signaling molecule in the body, exerting various biological effects through interaction with purinergic receptors and modulation of cellular signaling pathways.

Neurotransmitter Function: In the central nervous system, inosine acts as a neuromodulator and neurotransmitter, participating in synaptic transmission, neuronal excitability, and neurotransmitter release. It is involved in processes such as synaptic plasticity and neuronal survival.

Anti-inflammatory and Immunomodulatory Effects: Inosine exhibits anti-inflammatory and immunomodulatory properties, suppressing immune cell activation, cytokine production, and inflammatory responses. It may have therapeutic potential in autoimmune diseases and inflammatory conditions.

Neuroprotective Effects: In preclinical studies, inosine has shown neuroprotective effects against various neurodegenerative diseases and neurological disorders, including Parkinson's disease, Alzheimer's disease, and ischemic stroke. It may promote neuronal survival and function.

Cardioprotective Effects: Inosine has been studied for its potential cardioprotective effects, including the improvement of myocardial function, reduction of ischemia-reperfusion injury, and enhancement of cardiac recovery following cardiac events.

Exercise Performance: Inosine has been investigated for its potential role in enhancing exercise performance and endurance. It is thought to influence energy metabolism, oxygen utilization, and muscle function during physical activity.

Antioxidant Properties: Inosine exhibits antioxidant properties, scavenging free radicals and reactive oxygen species (ROS) that can damage cells and tissues. It may help protect against oxidative stress-related damage and promote cellular health.

Diagnostic Marker: Elevated levels of inosine in biological fluids, such as blood or urine, can serve as a diagnostic marker for certain medical conditions, including metabolic disorders, renal dysfunction, and ischemic events.

Dietary Source: Inosine is naturally present in certain foods, including meat, poultry, fish, legumes, and mushrooms. It contributes to the flavor and nutritional profile of these foods.

Supplementation: Inosine supplements are available and marketed for various purposes, including sports performance enhancement, cognitive support, and general health promotion. However, evidence supporting their efficacy and safety is limited, and caution should be exercised when using supplements.

Pharmacokinetics: After ingestion, inosine is rapidly absorbed from the gastrointestinal tract and metabolized in the liver. It is converted into other purine metabolites, such as uric acid, which are excreted primarily through the kidneys.

Research and Development: Ongoing research is exploring the therapeutic potential of inosine in various medical conditions, including neurological disorders, cardiovascular diseases, inflammatory conditions, and metabolic disorders. Clinical trials are needed to further evaluate its efficacy and safety.

Safety and Tolerability: Inosine is generally considered safe when consumed in dietary amounts or used as a supplement at recommended doses. However, high doses may cause adverse effects, including gastrointestinal discomfort, allergic reactions, and interactions with medications. It is important to consult a healthcare professional before using inosine supplements, especially in individuals with underlying medical conditions or taking medications.