Factory Direct Supply High Quality TNJONE 99% Purity Sitagliptin phosphate monohydrate 654671-77-9

Sitagliptin phosphate monohydrate is very effective in treating type 2 diabetes. As a new type of anti-diabetic drug, sitagliptin phosphate is blood sugar-dependent, has a moderate hypoglycemic effect, increases in-sulin secretion without hypoglycemia, effectively reduces hunger and other advantages, and has no nausea, vomiting, edema and increase Side effects such as body weight.

Name	Sitagliptin phosphate monohydrate
CAS NO.	654671-77-9
purity	99%
Standard packing material	Bag/Box
Appearance	White Powder
Shelf Life	2Years
storage condition and solubility	Inert atmosphere,Store in freezer, under -20°C;

Item	Standard	Result
Appearance	White or almost white crystalline powder	Almost white crystalline powder
Melting point	152-156°C	154.6-155.1°C
Specific optical rotation	-16° to -19°	-17.5°
Identification	(1)The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation,as obtained in the assay.	Complies
	(2)UV absorption Max. at 266nm.	Complies
	(3)IR spectra is consistent with CRS.	Complies
PH	4.5-6.5	5.7
Chloride	0.02% max	<0.02%
Fluorides	4.8%min	4.9%
Related substances	Individual impurity not more than 0.5%	0.35%
	Total impurities not more than 2.0%	0.76%
Water	0.5% max	0.13%
Residue on ignition	0.1%max	0.06%
Heavy metals	Less than or egual to 20 millionths	Less than20 millionths
Assay(C12H14Cl2FNO4S)	98.0%min	99.0%

Function&Application:

• 1.As a new type of antidiabetic drug, sitagliptin phosphate has the advantages of glucose dependence, moderate hypoglycemic effect, increased secretion without hypoglycemia, effectively alleviated hunger, and had no side effects such as nausea, vomiting, edema and increased body weight.
  2.Sitagliptin phosphate as a single drug treatment in patients with type II diabetes can significantly reduce the level of glycosylated hemoglobin (HbA1c).
  3.It is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which can improve the human body's ability to reduce high blood glucose level.

Shaanxi TNJONE Pharmaceutical Co., Ltd is a high-tech enterprise mainly engaged inthe development and sale of pharmaceutical chemical raw materials and relatedproducts.The company has advanced and perfect supporting system,forming advancedchemical synthesis technology, which can quickly meet the individual needs and serialdevelopment from suitable detection to industrial production.Qur business covers morethan 30 countries, most of customers from Europe, Southeast Asia and other countriesin the world, we can guarantee the quality and price. Our enterprise purpose is basedon the market, strengthen strength, take the road of scientific environmental protectionand sustainable development, rely on the country. The company has a strong financialstrength and a good business environment, can provide customers with quality,efficientand fast service.

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