Cosmetic/Food/Pharma Grade Sodium Hyaluronate White Powder CAS 9067-32-7 Hyaluronic acid

Sodium hyaluronate More Info

Sodium hyaluronate is the sodium salt form of hyaluronic acid, a naturally occurring biopolymer found in connective tissues, skin, and synovial fluid. It is well-known for its hydrating properties and is widely used in various medical and cosmetic applications.

Mechanism of Action

Sodium hyaluronate functions primarily as a humectant and viscoelastic agent:
Moisture Retention: It has a high capacity to attract and retain water, making it effective in hydrating tissues. This property helps to reduce dryness and improve skin elasticity.
Tissue Lubrication: In joints and other tissues, sodium hyaluronate acts as a lubricant, reducing friction between moving parts. This is particularly beneficial in synovial fluid within joints.
Wound Healing: It promotes tissue repair by acting as a protective barrier, facilitating the transport of growth factors to the site of injury and enhancing cellular migration and proliferation.

Applications

Sodium hyaluronate is utilized in various fields:
Ophthalmology: Used as an ophthalmic viscosurgical device during eye surgeries (e.g., cataract extraction) to maintain intraocular pressure and protect ocular tissues.
Orthopedics: Administered via intra-articular injections to alleviate pain associated with osteoarthritis by restoring synovial fluid viscosity.
Dermatology: Commonly found in topical formulations for skin hydration, wound healing, and as a component in dermal fillers for cosmetic procedures.
Cosmetics: Incorporated into skincare products to enhance moisture retention and improve skin texture.
Urology: Instilled intravesically for treating interstitial cystitis by replenishing the glycosaminoglycan layer of the bladder.

Routes of Administration

Sodium hyaluronate can be administered through various routes depending on its application:
Topical Application: Creams, gels, or serums applied directly to the skin for hydration or wound healing.
Intra-articular Injection: Injected directly into joints to relieve osteoarthritis symptoms.
Ophthalmic Drops: Used as eye drops for dry eyes or during surgical procedures.
Intravesical Instillation: Administered into the bladder for treating bladder conditions.

Safety and Side Effects

Sodium hyaluronate is generally considered safe; however, some side effects may include:
Topical Use: Mild irritation, redness, or allergic reactions at the application site can occur. In rare cases, more severe allergic reactions may happen.
Intra-articular Injections: Possible side effects include joint swelling, pain at the injection site, or transient increases in pain.
Ophthalmic Use: Temporary blurred vision or discomfort may occur after application of eye drops.

Pharmacokinetics

The pharmacokinetic properties of sodium hyaluronate vary based on its formulation and route of administration:
Absorption: When applied topically, it penetrates the skin but its absorption can vary based on molecular weight; lower molecular weight forms penetrate deeper into the skin layers.
Distribution: Sodium hyaluronate distributes widely in tissues where it exerts its hydrating and lubricating effects.
Metabolism: It is metabolized by hyaluronidase enzymes into smaller fragments that can be further degraded. The metabolic pathway varies depending on the tissue type and physiological conditions.
Elimination: The elimination half-life depends on the route of administration; for example, intra-articular injections may have prolonged effects due to slower clearance from joint spaces.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

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Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

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Q5. What HyperChem will provide after shipment?

For sample orders: 
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For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
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Cosmetic Ingredients
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HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.