Sucralose

• CAS No:

56038-13-2

• Formula:

C12H19Cl3O8

• Chemical Name:

Sucralose

Description

Sucralose is an intense organochlorine artificial sweetener.

White to off-white, practically odourless, crystalline powder.

Sucralose is a disaccharide derivative consisting of 4-chloro-4-deoxy-alpha-D-galactopyranose and 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose units linked by a glycosidic bond. It has a role as an environmental contaminant, a xenobiotic and a sweetening agent. It is a disaccharide derivative and an organochlorine compound.|Sucralose is an artificial sweetener used as a sugar substitute.

Sucralose Basic Attributes

Molecular Weight ：397.633

Exact Mass ：397.63

EC Number ：259-952-2

UNII ：96K6UQ3ZD4

NSC Number ：759272

DSSTox ID ：DTXSID1040245

Color/Form ：White to off white, crystalline powder|Anhydrous crystalline form: orthorhombic, needle-like crystals|Syrup

Characteristics

PSA ：128.84

XLogP3 ：-1.5

Appearance ：White crystal powder

Density ：1.375 g/cm

Melting Point ：130 °C

Boiling Point ：104-107 C

Flash Point ：358.7ºC

Refractive Index ：1.604

Water Solubility ：In water, 2.27X10+4 mg/L at 25 deg C (est)

Storage Conditions ：Hygroscopic, -20ºC Freezer, Under Inert Atmosphere

Vapor Pressure ：3.25X10-14 mm Hg at 25 deg C (est)

Toxicity ：LD50 orally in Rabbit: > 10000 mg/kg

Taste ：Intensely sweet taste

Henrys Law Constant ：Henry's Law constant = 3.99X10-19 atm-cu m/mol at 25 °C (est)

Collision Cross Section ：177.2 Ų [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|179.16 Ų [M-H]-

Experimental Properties ：Sugar equivalence value relative to sucrose = 600|In water ... stable to heat over a wide range of pH|Hydroxyl radical reaction rate constant = 5.42X10-11 cu cm/molec-sec at 25 °C (est)

Sucralose Use

A low-calorie artificial sweetener

Formulations ：Aqueous solutions

Manufacturing Info ：Chlorinated sucrose derivative with enhanced sweetness|Compared with dilute sucrose solution, sucralose is about 600 times sweeter. The sweetness is perceived with a slight delay and a lasting effect, similar to aspartame, and generally considered of good quality.|Solid sucralose is not fully stable, and slowly releases HCl, with discoloration. In contrast, aqueous solutions are highly stable, and it is marketed in this form.

Use Classification ：Food additives|Food Additives -> SWEETENER; -> JECFA Functional Classes

Food Additive Classes ：Food Additives -> SWEETENER;