MCPA 4.5%+ glyphosate 80%SP super weed killer factory price

MCPA 4.5%+ glyphosate 80%SP super weed killer factory price

NOMENCLATURE

MCPA

Common name MCPA (BSI, E-ISO, F-ISO, WSSA); 2,4-MCPA ((m) France); 2M-4Kh (USSR); metaxon* (former name, USSR); MCP (JMAF)

IUPAC name (4-chloro-2-methylphenoxy)acetic acid  

Chemical Abstracts name (4-chloro-2-methylphenoxy)acetic acid  

CAS RN [94-74-6]  EEC no. 202-360-6  Development codes BAS 010H; BAS 141H (both ); L065 (Marks)  

MCPA-dimethylammonium

CAS RN [2039-46-5]  

MCPA-2-ethylhexyl

CAS RN [29450-45-1]  

MCPA-sodium

CAS RN [3653-48-3], formerly [11100-01-9] and [11114-06-0]  EEC no. 222-895-9  

MCPA-butotyl

Mol. wt. 300.8  M.f. C15H21ClO4  Solubility Readily soluble in organic solvents.  

MCPA-dimethylammonium

Mol. wt. 245.7  M.f. C11H16ClNO3  

APPLICATIONS

Biochemistry Synthetic auxin (acting like indolylacetic acid).  Mode of action Selective, systemic, hormone-type herbicide, absorbed by the leaves and roots, with translocation. Concentrates in the meristematic regions, where it inhibits growth.  Uses Post-emergence control of annual and perennial broad-leaved weeds (including thistles and docks) in cereals (alone or undersown), herbage seed crops, flax, rice, vines, peas, potatoes, asparagus, grassland, turf, under fruit trees, and on roadside verges and embankments, etc., at 0.28-2.25 kg/ha. Control of broad-leaved and woody weeds in forestry. Control of aquatic broad-leaved weeds. Often used in combination with other herbicides. Phytotoxicity Phytotoxic to vines, vegetables, cotton, and ornamentals.  Formulation types EC; SL; SP.  

ANALYSIS

Product analysis (acid or salts) by i.r. spectrometry (AOAC Methods, 17th Ed., 971.07, CIPAC Handbook, 1985, 1C, 2137), by hplc (ibid., 1985, 1C, 2139; AOAC Methods, 17th Ed., 980.07) by liquid/liquid chromatography (CIPAC Handbook, 1985, C, 2138; 1980, 1A, 477), by glc of a derivative (CIPAC Handbook, 1985, 1C, 2143, 2257; 1994, F, 292-319) or by titration (ibid., 1985, 1C, 2137); esters by similar methods (ibid., 1985, 1C, 2145); FAO Specification 2/TC/S/F (1992). Mixtures with 2,3,6-TBA by titration or chromatography of a derivative (CIPAC Handbook, 1985, C, 2148). Free phenol impurity determined by glc (CIPAC Handbook, 1994, F, 197), hplc (ibid., 1994, F, 362) or electrochemically (ibid., 1994, F, 368). Residues determined by glc of a derivative (J. Lest, Anal. Methods Pestic., Plant Growth Regul. Food Addit., 1967, 5, 439; Anal. Methods Pestic. Plant Growth Regul., 1972, 6, 663) or by hplc (M. Meier et al., Fresenius' Z. Anal. Chem.,1989, 334(3), 235).  

MAMMALIAN TOXICOLOGY

IARC ref. 30, 41; Suppl. 7  class chlorophenoxy herbicides classified as 2B, based on epidemiology of production. More recent evidence (M. Kogevinas et al., Am. J. Epidemiol., 145(12), 1061 (1997)) relates this to dioxin contamination of early production. Not relevant to current processes.  

MCPA

Oral Acute oral LD50 for rats 700-1160 mg/kg.  Skin and eye Acute percutaneous LD50 for rats >4000 mg/kg. Not irritating to skin; irritating to eyes. Not a skin sensitiser.  Inhalation LC50 (4 h) for rats >6.36 mg/l.  NOEL (24 mo) for rats 20 ppm (c. 1.33 mg/kg daily), for mice 100 ppm (c. 18 mg/kg daily).  Water GV 2 mg/l (TDI 0.5 mg/kg b.w.).  Toxicity class WHO (a.i.) III; EPA (formulation) III  EC classification Xn; R22| Xi; R38, R41: (for salts and esters, Xn; R20/21/22)  

MCPA-2-ethylhexyl

Skin and eye A skin irritant. Not a skin sensitiser (guinea pigs).  Inhalation LC50 for rats >4.5 mg/l.  

ECOTOXICOLOGY

MCPA

Birds Acute oral LD50 for bobwhite quail 377 mg/kg. Sub-acute dietary LC50 (5 d) for bobwhite quail and mallard ducks >5620 ppm.  Fish LC50 (96 h) for rainbow trout 50-560, bluegill sunfish >150, carp 317, silverside 220 mg/l.  Daphnia LC50 (48 h) >190 mg/l.  Algae EC50 for Selenastrum capricornutum >392 mg/l.  Other aquatic spp. LC50 for pink shrimp (Panaeus duorarum) 231 mg/l.  Bees LD50 0.104 mg/bee.  Worms LD50 (14 d) for Eisenia foetida 325 mg/kg soil.  

ENVIRONMENTAL FATE

Animals In rats, following oral administration, MCPA is rapidly absorbed and excreted almost exclusively in the urine, with only a small proportion in the faeces. Only moderate metabolism occurs, and there is only a small amount of conjugate formation.  Plants In winter wheat, MCPA is hydroxylated at the methyl group with formation of 2-hydroxymethyl-4-chlorophenoxyacetic acid. This may be further degraded to the benzoic acid, prior to ring opening.  Soil/Environment In soil, degraded to 4-chloro-2-methylphenol, followed by ring hydroxylation and ring opening. DT50 <7 d after initial lag phase. Duration of residual activity in soil is c. 3-4 mo, following an application rate of 3 kg/ha.