Hot Selling 99% High Quality Yellow Powder Berberine hydrochloride CAS No.:633-65-8
TDS 3 Inquiries
633-65-8
Pharmaceutical Grade
99%
Shanghai
YH
1kg/bag,25kg/drum,25kg/bag
Yes
2025-03-09
Food Additives,Active Pharm Ingredients,Chem & Pharm Intermediates,Organic Intermediates
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceBerberine has shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells; MAPK and Wnt/β-catenin pathways affected by Berberine.IC50 value:Target: Anticancer agentThe plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecu
Berberine chloride (TN) is an organic molecular entity.|Berberine Chloride is the orally bioavailable, hydrochloride salt form of berberine, a quaternary ammonium salt of an isoquinoline alkaloid and active component of various Chinese herbs, with potential antineoplastic, radiosensitizing, anti-inflammatory, anti-lipidemic and antidiabetic activities. Although the mechanisms of action through which berberine exerts its effects are not yet fully elucidated, upon administration this agent appears to suppress the activation of various proteins and/or modulate the expression of a variety of genes involved in tumorigenesis and inflammation, including, but not limited to transcription factor nuclear factor-kappa B (NF-kB), myeloid cell leukemia 1 (Mcl-1), B-cell lymphoma 2 (Bcl-2), B-cell lymphoma-extra large (Bcl-xl), cyclooxygenase (COX)-2, tumor necrosis factor (TNF), interleukin (IL)-6, IL-12, inducible nitric oxide synthase (iNOS), intercellular adhesion molecule-1 (ICAM-1), E-selectin, monocyte chemoattractant protein-1 (MCP-1), C-X-C motif chemokine 2 (CXCL2), cyclin D1, activator protein (AP-1), hypoxia-inducible factor 1 (HIF-1), signal transducer and activator of transcription 3 (STAT3), peroxisome proliferator-activated receptor (PPAR), arylamine N-acetyltransferase (NAT), and DNA topoisomerase I and II. The modulation of gene expression may induce cell cycle arrest and apoptosis, and inhibit cancer cell proliferation. In addition, berberine modulates lipid and glucose metabolism.CertificatesBasic Info-
Product Name:
Berberine hydrochloride
Other Name:Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-,chloride (1:1);Berbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-,chloride;Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-,chloride;Berberine,chloride;Berberine hydrochloride;Berberinium chloride;NSC 646666;NSC 163088;Berberine IR;16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride;1082532-96-4
CAS No.:633-65-8
Molecular Formula:C20H18NO4.Cl
InChIKeys:InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M
Molecular Weight:371.81400
Exact Mass:371.09200
EC Number:211-195-9
UNII:UOT4O1BYV8
NSC Number:757795|163088|646666
DSSTox ID:DTXSID8024602
NCI Thesaurus Code:C87331
HScode:3003409000
Categories:
Characteristics-
PSA:
40.80000
XLogP3:0.10030
Appearance:yellow crystalline powder
Density:1.654g/cm3
Melting Point:214 °C
Water Solubility:soluble in cold water
Storage Conditions:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from
Toxicity:LD50 orl-rat: >15 g/kg KSRNAM 8,654,74
Collision Cross Section:175.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Food Additives,Active Pharm Ingredients,Chem & Pharm Intermediates,Organic Intermediates
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Location:
No.15 Qinling Avenue,Caotang Industrial Park,High-techZone,Xi'an Shaanxi China
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Payment Terms:
L/C,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
51-100
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Year of Establishment:
2024
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
Netherlands
Berberine Hydrochloride
1000 KG May 12, 2026 
India
Berberine hydrochloride
1000 KG Dec 7, 2023 
United States
Berberine HCl 95% Yellow Brown powder Arshine
25 KG Nov 20, 2023 Post an enquiry for this product
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