What is Dulaglutide ?
Dulaglutide (trade name: Trulicity) is a long-acting GLP-1 analog developed by Eli Lilly for subcutaneous injection once per week. It was approved in the United States for the treatment of type 2 diabetes in September 2014. From the structural point of view, dulaglutide replaces Gly at position 8 of GLP-1 (7-37) chain for Ala, Glu at position 22 for Gly, and ChemicalbookGly at position 36 for Arg, with a long average biological half-life. Up to 90h.InFebruary 2014, clinical results showed that the efficacy of dulaglutide was not inferior to liraglutide, and it was the first macromolecular GLP-1 analogue that was not inferior to liraglutide in efficacy. However, the frequency of dosing dulaglutide once/w can greatly improve patient compliance, and it is a new product with great potential to compete with liraglutide.
| Items | Specifications |
| Product name | Dulaglutide |
| CAS No. | 923950-08-7 |
| MF | / |
| MW | / |
| EINECS No. | 200-001-8 |
| Appearance | white powder |
| Shelf Life | 2 Years When Properly Stored |
| Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
Dulaglutide Function & Application
Dulaglutide is a medication used for the treatment of type 2 diabetes in combination with diet and exercise. It is also approved in the United States for the reduction of major adverse cardiovascular events in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors.
Dulaglutide was used in the treatment of type 2 diabetes mellitus. The clinical results showed that the efficacy of Dulaglutide was not inferior to that of liraglutide, and it was the first macromolecular GLP-1 analogue that was not inferior to that of liraglutide.However, duraglutide is a new product with great potential to compete with liraglutide because the dosing frequency of 1 time/W can greatly improve patient compliance.
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