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Home > Food Additives > Nutrition Supplements > L-Arginine for Sale > USP Standard Supplement L-Arginine CAS:74-79-3 for Injection Grade and Pharmacy Grade
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USP Standard Supplement L-Arginine CAS:74-79-3 for Injection Grade and Pharmacy Grade

TDS 52 Inquiries

Unit Price:

$18-20/KG FOB

Get Latest Price
CAS No.:

74-79-3

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1kg/Bag or other quantities

Price valid (until):

2026-08-31

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    Name L-Arginine
    CAS number 74-79-3
    Synonym

    L(+)-Arginine

    Related APIs # L-Lysine
    1. L-Citrulline
    2. L-Ornithine
    3. L-Histidine
    4. L-Norvaline
    5. Arginine Alpha-Ketoglutarate (AAKG)
    6. Arginine Hydrochloride
    7. Arginine Ethyl Ester
    8. Arginine Silicate
    9. Arginine Ketoisocaproate
    10. L-Glutamine
    11. L-Tyrosine
    12. L-Leucine
    13. L-Isoleucine
    14. L-Valine
    15. Beta-Alanine
    16. Taurine
    17. N-Acetyl-L-Carnitine
    18. Glycine Propionyl-L-Carnitine
    19. L-Carnitine L-Tartrate
    Description


    Introduction

    L-Arginine, a semi-essential amino acid, plays a pivotal role in numerous physiological processes, ranging from protein synthesis to immune function. Chemically designated as ​C₆H₁₄N₄O₂, it is classified as a ​conditionally essential amino acid, meaning that while the body can synthesize it under normal conditions, supplementation becomes critical during periods of stress, injury, or illness. This article delves into its chemical mechanisms, physiological roles, applications, and usage guidelines.

    ​1. Chemical Structure and Mechanisms
    L-Arginine is a ​basic, positively charged amino acid due to its ​guanidino group (–NH–C(NH₂)–NH₂), which distinguishes it from other amino acids. Its structure comprises an α-amino group, a carboxyl group, and a side chain containing three methylene groups (–CH₂–) terminated by the guanidino moiety. This unique structure enables it to participate in diverse biochemical pathways.

    Key Biochemical Pathways:

    Urea Cycle:
    In the liver, L-arginine is integral to the ​urea cycle, where it acts as an intermediate. It combines with ​ornithine to produce ​citrulline, which is later converted back to arginine. This cycle detoxifies ammonia, a byproduct of protein metabolism, by converting it into urea for excretion.

    ​Protein Synthesis and Post-Translational Modifications:
    As a building block for proteins, L-arginine contributes to the structure of enzymes, hormones, and signaling molecules. Additionally, its guanidino group participates in ​post-translational modifications, such as ​arginylation, which influences protein stability and function.

    ​Creatine and Polyamine Synthesis:
    L-Arginine is a precursor for ​creatine, a molecule essential for ATP regeneration in muscle and brain tissues. It also contributes to the synthesis of ​polyamines (e.g., spermidine and spermine), which regulate cell growth, DNA stability, and apoptosis.

    ​2. Physiological Roles and Benefits
    L-Arginine’s versatility stems from its involvement in multiple systems:

    ​Cardiovascular Health: By boosting NO production, it enhances vasodilation, reduces blood pressure, and improves endothelial function. Studies suggest it may alleviate symptoms of angina, atherosclerosis, and hypertension.
    ​Immune Function: It modulates T-cell activity and macrophage function, enhancing the body’s defense against pathogens.
    ​Wound Healing: It accelerates tissue repair by promoting collagen synthesis and angiogenesis.
    ​Hormonal Regulation: It stimulates the release of insulin, growth hormone, and prolactin, aiding metabolism and growth.
    ​Reproductive Health: In males, it improves sperm motility and erectile function by increasing blood flow to genital tissues.
    ​3. Sources and Dietary Requirements
    While the body synthesizes L-arginine from ​citrulline (via the intestinal-renal axis), dietary sources remain vital. Rich sources include:

    ​Animal proteins: Red meat, poultry, fish (e.g., salmon, tuna), and dairy products.
    ​Plant-based foods: Soybeans, lentils, chickpeas, nuts (walnuts, almonds), and seeds.
    The average daily requirement for adults is ​2–5 grams, though this varies with age, health status, and physical activity. Deficiency, though rare, manifests as impaired immunity, hair loss, and poor wound healing.

    ​4. Clinical and Supplemental Use
    L-Arginine is widely used in medical and supplemental contexts:

    A. Therapeutic Applications

    ​Cardiovascular Diseases:
    Intravenous or oral L-arginine (3–6 g/day) is prescribed to improve endothelial dysfunction in coronary artery disease. However, its efficacy in acute myocardial infarction remains debated.
    ​Erectile Dysfunction (ED):
    As a precursor to NO, it relaxes penile blood vessels. Doses of 3–5 g/day may enhance erectile response, though results are less consistent than pharmaceuticals like sildenafil.
    ​Immune Support in Critical Care:
    Arginine-enriched formulas are used in trauma or post-surgery recovery to reduce infections and hospital stays.
    ​Hypertension and Preeclampsia:
    Some studies highlight its role in lowering blood pressure in pregnant women with preeclampsia.
    B. Sports Nutrition and Bodybuilding
    Athletes use L-arginine (2–10 g/day) to:

    Increase ​nitric oxide levels, enhancing oxygen/nutrient delivery to muscles.
    Delay fatigue via ammonia detoxification (by converting it to urea).
    Stimulate growth hormone secretion, aiding muscle growth.
    C. Cosmetic and Dermatological Use
    Topical creams containing L-arginine improve skin hydration and elasticity by boosting collagen synthesis.

    ​5. Safety and Side Effects
    L-Arginine is generally safe at recommended doses but may cause:

    Gastrointestinal distress (nausea, diarrhea).
    Hypotension in individuals with low blood pressure.
    Exacerbation of herpes outbreaks (as the virus utilizes arginine for replication).
    Contraindications:

    Avoid in patients with severe liver/kidney disease.
    Use cautiously with antihypertensive or nitrate medications (risk of additive vasodilation).
    ​6. Future Research Directions
    Emerging studies explore L-arginine’s role in:

    ​Cancer therapy: Modulating tumor-associated immune cells.
    ​Neuroprotection: Mitigating cognitive decline via NO-mediated cerebral blood flow.
    ​Aging: Enhancing mitochondrial function and reducing oxidative stress.
    Conclusion
    L-Arginine is a multifunctional amino acid with profound implications for human health. Its role in nitric oxide synthesis bridges cellular signaling and systemic physiology, making it indispensable for cardiovascular, immune, and metabolic functions. While dietary intake suffices for most individuals, targeted supplementation holds promise in clinical and performance settings. Ongoing research continues to unravel its therapeutic potential, solidifying its status as a cornerstone of nutritional biochemistry.


    Molecular Formula C6H14N4O2
    Molecular Weight 174.2 g/mol
    Appearance White crystalline powder
    Quality Standard Enterprise standard; 98%- 102%(ICP-AES)
    Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
    Storage Condition Dry, dark and at 0-28 for short term (days to weeks) or -5-8 for long term (months to years).
    Shelf Life >2 years if stored properly
    Sample package Double plastic bags inside, fiber drum outside, any quantity available.
    Commercial package Aluminium Tin, Fiber drum
    Origin China


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    FAQ

    Q1. What is the Hyper chem payment term?
    T/T advance
    LC at sight
    DP at sight
    Trade assurance 
    Money gram 

     

    Q2. What is Hyper chem shipment policy?
    Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
    For non-ready stock, please contact the Hyper Chem sales team to negotiate.

     

    Q3. What hyper chem will provide after shipment?
    For sample orders: 
    After shipment is done, an timely email including:

    Track details (Fedex /TNT/DHL/EMS Track number)

    Package photo

    COA, MSDS, etc 

    Dispatch date & Estimated arriving time

    Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided
    in scan-copy and original, to help customers complete the customs clearance process.

     

    Q4. What is Hyper Chem shipment term?

    By Express   
    DHL  FedEx  TNT  EMS                               
    Fast:5 days around                             
    High cost, door to door service

    By Air                                         
    Suitable for more than 50kg 
    Fast :3-7 days Hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Slow:7-45 days, Low cost, port to port, professional broker needed 
    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

     

    Q5. Does hyper chem provide a shipment return policy?
    Yes, we have.
    Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied  within 45 days of purchase for a full refund to:

     

    Q6. What is hyper chem After-sales service
    •Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
    • Customer Support: Shipment clearance support, quality issue support
    • Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

     

     

     

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

     

    Among them, our key client industrial sectors around the global are:

     

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply

     

    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

    Certificates

    Basic Info
    Product Name:

    L-Arginine

    Other Name:

    L-Arginine;Arginine,L-;Arginine;Pentanoic acid,2-amino-5-[(aminoiminomethyl)amino]-,(S)-;L-(+)-Arginine;(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid;L-Norvaline,5-[(aminoiminomethyl)amino]-;L-Ornithine,N5-(aminoiminomethyl)-;L-α-Amino-δ-guanidinovaleric acid;L-Arg;NSC 206269;L-arginine C Grade;A 0526;(2S)-2-Amino-5-(diaminomethylideneamino)pentanoic acid;42: PN: WO2020027640 SEQID: 105 claimed protein;42: PN: KR20200014684 SEQID: 105 claimed sequence;117: PN: WO2021061872 SEQID: 117 claimed protein;142-49-4;7004-12-8;154605-63-7;154605-67-1;667422-95-9;1332377-47-5

    CAS No.:

    74-79-3

    Molecular Formula:

    C6H14N4O2

    InChIKeys:

    InChIKey=ODKSFYDXXFIFQN-BYPYZUCNSA-N

    Molecular Weight:

    174.2

    Exact Mass:

    174.20

    BRN:

    1725413

    EC Number:

    200-811-1

    HScode:

    29252000

    Categories:

    Nutrition Supplements

    Characteristics
    PSA:

    128

    XLogP3:

    -4.2

    Appearance:

    white powder

    Density:

    1.10 g/cm3

    Melting Point:

    244 °C

    Boiling Point:

    409.1°C at 760 mmHg

    Flash Point:

    176.1±30.7 °C

    Refractive Index:

    1.601

    Water Solubility:

    H2O: 148.7 g/L (20 ºC)

    Storage Conditions:

    Storeat0-5

    Toxicity:

    Reference value: peritoneal-rat LD50: 3793 mg/kg

    Flammability characteristics:

    Flammable; burning produces toxic nitrogen oxide fumes

    Specific rotation:

    27.1 º (c=8, 6N HCl)

    PH:

    Strongly alkaline

    PKA:

    2.24(at 0 °C)

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    52 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Factory Bulk Amino Acid USP Bp Ep CAS 74-79-3 L-Arginine/ L Arginine

    50 KG Jul 14, 2023
    India

    L-Arginine 

    1.00 KG Oct 8, 2024
    India

    L-Arginine

    50.00 KG Jan 29, 2024
    India

    L-Arginine

    20.00 MT Dec 13, 2023
    Turkey

    L-ARGININE

    1 MT Feb 4, 2026
    Austria

    L-arginine

    5000 MG Jan 19, 2026
    India

    L-Arginine

    1 MT Apr 23, 2025
    United Kingdom

    L-Arginine

    1.00 20' Fcl Apr 2, 2025
    Thailand

    L-Arginine

    1 KG Feb 3, 2025
    Russia

    L-arginine

    25 KG Sep 24, 2024
    India

    L-Arginine

    25.00 KG Sep 6, 2024
    Israel

    L-ARGININE FOOD GRADE

    25 KG Apr 8, 2024
    Romania

    L-ARGININE

    2 MT Mar 12, 2024
    India

    L-Arginine

    50 KG Feb 6, 2024
    Turkey

    L-Arginine

    1 TON Nov 17, 2023
    Australia

    L-Arginine Base 99% HAIDE BIOTECH

    25 KG Aug 3, 2023
    South Korea

    L-Arginine

    6 MT Jun 30, 2026
    India

    L Arginine Base USP

    300.00 KG May 18, 2026
    Slovenia

    L-ARGININE

    400 KG Jan 9, 2026
    India

    L- arginine

    100.00 KG Oct 27, 2025
    Post an enquiry for this product
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