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High Quality USP Antibiotic White Powder Tobramycin CAS 32986-56-4 with good price and fast delivery

Name: High Quality USP Antibiotic White Powder Tobramycin CAS 32986-56-4 with good price and fast delivery
Brand: HyperChem
SKU: pr2504281095
Price: 1000 USD
Availability: InStock

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CAS No.:

32986-56-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

1kg/Bag, 25kg/drum

Price valid (until):

2025-05-28

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Tobramycin
CAS number	32986-56-4
EINECS number	251-322-5
Synonym	Tobramycin; Tobramycin sulfate; (2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol; 1-epitobramycin; 3’-deoxykanamycinb; 4-[2,6-diamino-2,3,6-trideoxy-alpha-d-glycopyranosyl]-6-[3-amino-3-deoxy-alpha; 6-trideoxy-alpha-d-ribo-hexopyranosyl-(1-4))-2-deoxy-; d-6-trideoxy-alpha-d-ribohexopyranosyl-(1-6))-2-deoxy;d-6-tyrideoxy-alpha-d-ribohexopyranosyl-(1-6))-2-deoxy;
Description	Tobramycin is an effective antibiotic commonly used in the management and treatment of various systemic and ocular infections. As an aminoglycoside antibiotic, tobramycin is active against aerobic gram-negative bacteria, including Pseudomonas aeruginosa. Tobramycin binds to the 16s ribosomal RNA component of the bacterial 30s ribosomal unit, inhibiting the initiation step of translation. By binding to the A-site, tobramycin induces mistranslation and causes transfer RNA to misread the codon, thus causing incorrect delivery of aminoacyl units. Incorrectly synthesized proteins build up inside the cell, disrupting the cell membrane and various cellular processes; this mechanism of action designates tobramycin as a bactericidal agent.
Structure
Molecular Formula	C18H37N5O9
Molecular Weight	467.52 g/mol
Appearance	Solid powder
Quality Standard	USP Standard
Assay	≥98%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Store in cool place. Keep container tightly closed in a dry and well ventilated place.
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Tobramycin More Info

Tobramycin is an aminoglycoside antibiotic with potent activity against a range of Gram-negative and some Gram-positive bacteria, notably Pseudomonas aeruginosa. It is used in various formulations, including intravenous/intramuscular injection, inhalation, and topical eye preparations.

Mechanism of Action

Tobramycin binds to bacterial 30S (and to some extent 50S) ribosomal subunits, preventing the formation of the functional 70S initiation complex. This blocks mRNA translation, inhibits protein synthesis, and leads to bacterial cell death. It exhibits both immediate bactericidal effects (through membrane disruption) and delayed effects (via impaired protein synthesis).

Clinical Uses

Inhalation: Management of chronic Pseudomonas aeruginosa lung infections in cystic fibrosis patients.
Injection (IV/IM): Treatment of serious infections such as septicemia, meningitis, lower respiratory tract, abdominal, urinary tract, skin, bone, and joint infections caused by susceptible bacteria.
Ophthalmic: Treatment of external eye infections (e.g., conjunctivitis) due to susceptible organisms.

Dosage and Administration

Injection: Usual adult dose is 3 mg/kg/day divided every 8 hours; severe infections may require up to 5 mg/kg/day, with dose reduction as soon as possible. Both IV and IM routes are used, and dosing must be adjusted for renal function. Duration is typically 7–10 days.
Inhalation: Used in cystic fibrosis, dosing and duration depend on patient age and lung function.
Ophthalmic: As directed for topical infections.

Safety and Side Effects

Common: Nausea, vomiting, diarrhea, pain at injection site, headache, fever, tiredness.
Serious: Nephrotoxicity (kidney damage), ototoxicity (hearing loss, balance problems), severe allergic reactions, and rare severe skin reactions (e.g., Stevens-Johnson syndrome).
Monitoring: Renal, auditory, and vestibular function should be monitored, especially with prolonged therapy or high doses.

Pharmacokinetics

Absorption: Not orally bioavailable; administered parenterally or by inhalation/topically. Inhaled forms achieve high sputum concentrations with minimal systemic absorption.
Distribution: Large apparent volume of distribution in cystic fibrosis patients; negligible protein binding.
Metabolism: Not appreciably metabolized.
Elimination: Excreted unchanged in urine; serum half-life ~3 hours after inhalation.
Clearance: Primarily renal; adjust dose in renal impairment.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Certificates

Basic Info

Product Name:

Tobramycin

Other Name:

D-Streptamine,O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-;O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-D-streptamine;Nebramycin factor 6;Tobramycin;3′-Deoxykanamycin B;Nebramycin 6;Nebramycin VI;Deoxykanamycin B;Tobramycetin;Tobramicin;Tobralex;Tobrex;Tobramaxin;NF 6;Tobradistin;Tobracin;NSC 180514;Tobramax;Tobrin;Vantobra;Tobi Podhaler;11098-01-4;11111-45-8;34337-51-4;37321-13-4;54330-95-9;70322-33-7

CAS No.:

32986-56-4

Molecular Formula:

C18H37N5O9

InChIKeys:

InChIKey=NLVFBUXFDBBNBW-PBSUHMDJSA-N

Molecular Weight:

467.51

Exact Mass:

467.51

EC Number:

251-322-5

UNII:

VZ8RRZ51VK

NSC Number:

757352

DSSTox ID:

DTXSID8023680

NCI Thesaurus Code:

C62082

Color/Form:

White to off-white powder|Crystals

ATC Code:

J01GB01|J - Antiinfectives for systemic use|S - Sensory organs

HScode:

29419090

Categories:

Antibiotics

Characteristics

PSA:

268

XLogP3:

-6.2

Appearance:

white to off-white

Density:

1.5±0.1 g/cm3

Melting Point:

164 °C

Boiling Point:

741.6°C at 760 mmHg

Flash Point:

422.8±32.9 °C

Refractive Index:

1.651

Water Solubility:

H2O: 50 mg/mL, clear, faintly yellow

Storage Conditions:

2-8°C

Vapor Pressure:

2.37X10-21 mm Hg at 25 deg C (est)

Toxicity:

LD50 in mice, rats (mg/kg): 441, 969 s.c. (Welles)

Specific rotation:

D20 +129° (c = 1 in water)

PH:

Basic substance

Henrys Law Constant:

Henry's Law constant = 2.24X10-39 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKb1 = 8.6; pKb2 = 8.8; pKb3 = 9.0 (amines) (est)

Experimental Properties:

Hygroscopic

See More Tobramycin Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tobramycin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bulgaria	Tobramycin powder CAS 32986-56-4	50 G	Oct 22, 2024
India	Tobramycin	5 MT	Nov 14, 2025
Pakistan	Tobramycin	1 KG	Mar 6, 2025
Pakistan	Tobramycin	2	Feb 23, 2024
Bangladesh	Tobramycin	1 KG	Apr 13, 2026

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High Quality USP Antibiotic White Powder Tobramycin CAS 32986-56-4 with good price and fast delivery

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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