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API Paromomycin sulfate

Name: API Paromomycin sulfate
Brand: Hyper Chem
SKU: pr2505301053
Price: 650 USD
Availability: InStock

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CAS No.:

1263-89-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2025-06-30

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Paromomycin sulfate
CAS number	1263-89-4
Related CAS	1263-89-4 (sulfate) 7542-37-2 (free)
Synonym	Paromomycin Sulfate, Paromomycin, FI 5853, FI-5853, FI5853, Humatin, Aminosidin
Description	Paromomycin sulfate is an aminoglycoside antimicrobial agent derived from Streptomyces sp. AG-P 1441. Paromomycin likely induced resistance as confirmed by the expression of pathogenesis-related genes: PR-1, β-1,3-glucanase, chitinase, PR-4, peroxidase, and PR-10, which enhanced plant defense against P. capsici in chili pepper.
Molecular Formula	C₂₃H₄₇N₅O₁₈S
Molecular Weight	713.706
Appearance	White to off-white solid powder.
Quality Standard	USP, EP, BP, CP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 – 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Paromomycin sulfate More Info

Paromomycin sulfate is an aminoglycoside antibiotic that is poorly absorbed when taken orally. It works by binding to the 30S ribosomal RNA and inhibiting protein synthesis in susceptible organisms.

Uses

Intestinal Amebiasis: It is commonly used to treat both acute and chronic intestinal amebiasis, a parasitic infection caused by Entamoeba histolytica. The typical dosage is 25–35 mg/kg daily, divided into three doses, for 5–10 days.

Hepatic Coma: Paromomycin is also used in combination with other medicines to help reduce the symptoms of hepatic coma, a complication of liver disease. The usual dosage for adults is 4000 mg per day, divided into smaller doses, for 5–6 days.

Other Parasitic Infections: It has been used to treat infections caused by Giardia lamblia and Dientamoeba fragilis, with varying degrees of efficacy. Additionally, it has been suggested for the treatment of Cryptosporidium infections in HIV patients, although its effectiveness in this context is not well-established.

Administration

Paromomycin sulfate is available in capsule form and should be taken exactly as prescribed by a doctor. It is best taken with food to reduce gastrointestinal side effects. The medicine works best when there is a constant amount in the blood, so it is important to take it on a regular schedule.

Side Effects

Common side effects include gastrointestinal issues such as abdominal cramps, diarrhea, nausea, and vomiting. These side effects may subside as the body adjusts to the medication. In rare cases, systemic administration can lead to ototoxicity and nephrotoxicity. However, since paromomycin is poorly absorbed, these systemic side effects are less common with oral administration.

Precautions

Regular medical check-ups are important to monitor the progress of treatment and to ensure the medicine is working properly. If symptoms do not improve within a few days or worsen, patients should consult their doctor. Paromomycin sulfate is contraindicated in individuals with renal failure due to the risk of nephrotoxicity.

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Certificates

Basic Info

Product Name:

Paromomycin sulfate

Other Name:

D-Streptamine,O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-,sulfate (1:?);D-Streptamine,O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-,sulfate (salt);D-Streptamine,O-2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-,sulfate (salt);Humycin sulfate;Paromomycin sulfate;Aminosidine sulfate;Aminosidin sulfate;Humatin;Gabbroral;Sinosid;Paramicina;Farmiglucin;Farminosidin;Pargonyl;Paricina;Aminoxidin;FI 5853;1600 Antibiotic;Humagel;1405-13-6;11048-06-9;14963-45-2;42438-81-3;51981-74-9

CAS No.:

1263-89-4

Molecular Formula:

C23H45N5O14.xH2O4S

InChIKeys:

InChIKey=LJRDOKAZOAKLDU-UDXJMMFXSA-N

Molecular Weight:

713.71

Exact Mass:

713.263672

EC Number:

215-031-7

DSSTox ID:

DTXSID5047829

Categories:

Inhibitors

Characteristics

PSA:

430

Appearance:

powder

Melting Point:

145 °C (decomp)

Boiling Point:

1059.2°C at 760 mmHg

Flash Point:

522.2ºC

Water Solubility:

H2O: 50 mg/mL store stock solution at 2-8°C. Stable at 37°C for 5 days.

Storage Conditions:

0-6°C

Toxicity:

Oral-rat LD50: 21620 mg/kg; Oral-Mouse LD50: 23500 mg/kg

Flammability characteristics:

Flammable; burning produces toxic nitrogen oxides and sulfur oxide fumes

Specific rotation:

D25 +50.5° (c = 1.5 in water pH 6)

See More Paromomycin sulfate Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Paromomycin sulfate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
Netherlands	PAROMOMYCIN SULFATE 99% White or vials PAROMOMYCIN SULFATE SALT ParoMoMycin sulphate raw powder	0.01 KG	Jul 2, 2023
The Dominican Republic	Paromomycin sulfate USP35 supplier Pharmaceutical API made in china	5 G	Sep 7, 2023
Panama	Paramomycin Sulfate	150 KG	May 30, 2025
India	Paromomycin sulphate	1.00 KG	Mar 24, 2025

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