Asenapine RC00295
65576-45-6
Pharmaceutical Grade
98%
中国
Royalchem
25kg/drum
2025-12-31
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionBasic Info
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Product Name:
Asenapine
Other Name:1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole,5-chloro-2,3,3a,12b-tetrahydro-2-methyl-,(3aR,12bR)-rel-;1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole,5-chloro-2,3,3a,12b-tetrahydro-2-methyl-,trans-;rel-(3aR,12bR)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole;Asenapine;Saphris;Sycrest;Alkepin;135882-95-0
CAS No.:65576-45-6
Molecular Formula:C17H16ClNO
InChIKeys:InChIKey=VSWBSWWIRNCQIJ-PTTDRDKLNA-N
Molecular Weight:285.772
Exact Mass:285.77
EC Number:265-829-4
DSSTox ID:DTXSID8049048
Color/Form:White to off-white powder
ATC Code:N05AH05|N - Nervous system
HScode:2934999090
Categories:
Characteristics-
PSA:
12.47000
XLogP3:4.31
Appearance:COA
Density:1.231
Boiling Point:357.9±42.0 °C at 760 mmHg
Flash Point:170.2±27.9 °C
Refractive Index:1.610
Water Solubility:In water, 0.98 mg/L at 25 °C (est)
Storage Conditions:Store at +4°C
Vapor Density:1.83X10-6 mm Hg at 25 °C (est)
Dissociation Constants:pKa = 9.64 (amine) (est)
Collision Cross Section:167.6 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Experimental Properties:Crystals, mp 141-145 °C; uv max (ethanol): 270 nm (e 1900). Solubility at 21 °C (g/L): water 3, ethanol 30, methanol 250, acetone 125, ethyl acetate 10, dichloromethane 250, hexane <1. pH at 20 °C (0.1% solution in water): 4.56. pH at 23 °C (saturated solution 5.8 g/L): 4.43. pKa1 <3; pKa2 = 7.52, pKa3 = 8.51 /Asenapine maleate/|log Kow = 6.33 at 37 °C|Hydroxyl radical reaction rate constant = 9.24X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
